中国肿瘤临床
中國腫瘤臨床
중국종류림상
CHINESE JOURNAL OF CLINICAL ONCOLOGY
2014年
19期
1259-1263
,共5页
宋国慧%孟凡书%白文龙%靳国梁%李东方
宋國慧%孟凡書%白文龍%靳國樑%李東方
송국혜%맹범서%백문룡%근국량%리동방
食管肿瘤%癌前状态%高危人群%早诊早治%筛查
食管腫瘤%癌前狀態%高危人群%早診早治%篩查
식관종류%암전상태%고위인군%조진조치%사사
esophageal neoplasms%precancerous conditions%risk population%early detection%screening
目的：了解磁县食管癌高发区居民食管癌前状态及病变的分布情况，为该病的病因及二级预防提供依据。方法：收集磁县2005年1月至2009年12月完成的40～69岁人群的食管癌早诊早治内镜筛查资料，筛查采用内镜碘染色指示性活检，并对符合对象按性别、年龄组统计食管癌癌前状态及病变的检出率。结果：纳入分析队列筛查对象11423例，食管活检率66.90%。食管鳞状上皮轻度、中度、重度异型增生检出率分别为11.84%、2.66%、1.04%，原位癌检出率为0.40%，鳞癌可能有浸润的患者检出率为0.04%、黏膜内鳞状细胞癌为0.37%，浸润性鳞癌为0.17%。平均重度异型增生以上及癌的检出率为2.01%。结论：磁县食管癌高发区40～69岁人群存在大量无症状癌前病变及癌症患者，年龄和性别与检出率关系密切。
目的：瞭解磁縣食管癌高髮區居民食管癌前狀態及病變的分佈情況，為該病的病因及二級預防提供依據。方法：收集磁縣2005年1月至2009年12月完成的40～69歲人群的食管癌早診早治內鏡篩查資料，篩查採用內鏡碘染色指示性活檢，併對符閤對象按性彆、年齡組統計食管癌癌前狀態及病變的檢齣率。結果：納入分析隊列篩查對象11423例，食管活檢率66.90%。食管鱗狀上皮輕度、中度、重度異型增生檢齣率分彆為11.84%、2.66%、1.04%，原位癌檢齣率為0.40%，鱗癌可能有浸潤的患者檢齣率為0.04%、黏膜內鱗狀細胞癌為0.37%，浸潤性鱗癌為0.17%。平均重度異型增生以上及癌的檢齣率為2.01%。結論：磁縣食管癌高髮區40～69歲人群存在大量無癥狀癌前病變及癌癥患者，年齡和性彆與檢齣率關繫密切。
목적：료해자현식관암고발구거민식관암전상태급병변적분포정황，위해병적병인급이급예방제공의거。방법：수집자현2005년1월지2009년12월완성적40～69세인군적식관암조진조치내경사사자료，사사채용내경전염색지시성활검，병대부합대상안성별、년령조통계식관암암전상태급병변적검출솔。결과：납입분석대렬사사대상11423례，식관활검솔66.90%。식관린상상피경도、중도、중도이형증생검출솔분별위11.84%、2.66%、1.04%，원위암검출솔위0.40%，린암가능유침윤적환자검출솔위0.04%、점막내린상세포암위0.37%，침윤성린암위0.17%。평균중도이형증생이상급암적검출솔위2.01%。결론：자현식관암고발구40～69세인군존재대량무증상암전병변급암증환자，년령화성별여검출솔관계밀절。
Objective:To investigate the distribution of precancerous conditions and lesions of high-risk population in the high-in-cidence area of esophageal cancer in Ci County, Hebei Province. Methods:Esophageal cancer was detected early in 40 to 69 year old patients in Ci Xian through endoscopic screening data and endoscopic screening using iodine staining and indicative biopsy. The pa-tients were classified according to gender, age group, statistical esophageal precancerous condition, and lesion detection rate. Results:The analysis included 11 423 cases by screening queue, and the esophageal biopsy rate was 66.90%. The detection rates of squamous epithelium with mild, moderate, and severe dysplasia were 11.84%, 2.66%, and 1.04%, respectively. DCIS detection rate was 0.40%in patients with squamous cell carcinoma. The detection rate of the patients had been infiltrated by the squamous cell carcinoma was 0.04%.The rate of the squamous cell carcinoma within the mucosa was 0.37%.The rate of the infiltration squamous cell carcinoma was 0.17%. The detection rate of the hyperplasia above average severe dysplasia and cancer was 2.01%. Conclusion: High incidence of esophageal precancerous lesions was found in the Ci County aged 40 to 69. A large number of asymptomatic patients with cancer were detected. Age and sex are closely related to detection rate.
