CAJ | 학술논문

目的：探讨高血压病患者血液流变学指标变化及其临床意义。方法应用北京赛科希德生产的SA-6000型全自动血液流变仪测定150例高血压病患者与80名健康成人的全血黏度、血浆黏度、红细胞压积、红细胞聚集指数、红细胞刚性指数及红细胞变形指数并进行比较。结果与健康者相比，高血压病患者全血黏度、红细胞压积、红细胞聚集指数、红细胞刚性指数及红细胞变形指数均增高（P＜0.05或P＜0.01），其中男性高血压病患者血浆黏度亦增高（P＜0.05）。结论高血压病患者血液呈高黏滞状态。血液流变学指标检测对于了解高血压病临床病理变化和指导治疗具有重要意义。
목적：탐토고혈압병환자혈액류변학지표변화급기림상의의。방법응용북경새과희덕생산적SA-6000형전자동혈액류변의측정150례고혈압병환자여80명건강성인적전혈점도、혈장점도、홍세포압적、홍세포취집지수、홍세포강성지수급홍세포변형지수병진행비교。결과여건강자상비，고혈압병환자전혈점도、홍세포압적、홍세포취집지수、홍세포강성지수급홍세포변형지수균증고（P＜0.05혹P＜0.01），기중남성고혈압병환자혈장점도역증고（P＜0.05）。결론고혈압병환자혈액정고점체상태。혈액류변학지표검측대우료해고혈압병림상병리변화화지도치료구유중요의의。
Objective To investigate the changes of hemorheological indicators and the clinical significance in hypertensives. Methods SA-6000 automatic blood rheometer produced by Beijing Succeeder Company was used to measure the blood viscosity, plasma viscosity, hematocrit, erythrocyte aggregation index, erythrocyte rigidity index and erythrocyte deformation index in 150 hypertension patients and 80 healthy adults. Results Compared to the health controls, the blood viscosity, hematocrit, erythrocyte aggregation index, erythrocyte rigidity index and erythrocyte deformation index in hypertension patients were increased (P<0.05 or P<0.01). Plasma viscosity in male hypertension patients was also increased (P<0.05). Conclusion Blood of hypertensives is in highly viscous state. Testing of hemorheological indicators is important to know the clinical pathological changes of hypertension and to guide treatment.