中国血液流变学杂志
中國血液流變學雜誌
중국혈액류변학잡지
CHINESE JOURNAL OF HEMORHEOLOGY
2014年
1期
60-63
,共4页
纪红梅%李明哲%崔鹭%高天舒
紀紅梅%李明哲%崔鷺%高天舒
기홍매%리명철%최로%고천서
新诊断2型糖尿病%冠心病%生化指标
新診斷2型糖尿病%冠心病%生化指標
신진단2형당뇨병%관심병%생화지표
newly diagnosed type 2 diabetes%coronary heart disease%biochemical indicator
目的：探讨新诊断2型糖尿病合并冠心病患者血糖、血脂、糖化血红蛋白（HbA1c）特点。方法选取38例新诊断2型糖尿病合并冠心病患者，并以37例单纯新诊断2型糖尿病患者，28例单纯冠心病患者以及37名健康对照进行研究。血糖采用葡萄糖氧化酶法，血脂分析采用酶法，HbA1c测定方法为离子交换高效液相色谱（HPLC）法。结果新诊断2型糖尿病合并冠心病患者HbA1c、Lp(a)明显高于其他三组（P＜0.01），FPG、LDL-C、TC和TG较冠心病组和对照组差异有统计学意义（P＜0.01）。新诊断2型糖尿病组FPG、HbA1c、TC和TG较冠心病组和对照组差异有统计学意义（P＜0.01）， Lp(a)较冠心病组差异有统计学意义（P＜0.01），LDL-C较对照组差异有统计学意义（P＜0.01）。冠心病组年龄、Lp(a)和LDL-C较对照组差异有统计学意义（P＜0.01）。结论新诊断2型糖尿病患者在诊断初期就应重视血脂谱的筛查。
目的：探討新診斷2型糖尿病閤併冠心病患者血糖、血脂、糖化血紅蛋白（HbA1c）特點。方法選取38例新診斷2型糖尿病閤併冠心病患者，併以37例單純新診斷2型糖尿病患者，28例單純冠心病患者以及37名健康對照進行研究。血糖採用葡萄糖氧化酶法，血脂分析採用酶法，HbA1c測定方法為離子交換高效液相色譜（HPLC）法。結果新診斷2型糖尿病閤併冠心病患者HbA1c、Lp(a)明顯高于其他三組（P＜0.01），FPG、LDL-C、TC和TG較冠心病組和對照組差異有統計學意義（P＜0.01）。新診斷2型糖尿病組FPG、HbA1c、TC和TG較冠心病組和對照組差異有統計學意義（P＜0.01）， Lp(a)較冠心病組差異有統計學意義（P＜0.01），LDL-C較對照組差異有統計學意義（P＜0.01）。冠心病組年齡、Lp(a)和LDL-C較對照組差異有統計學意義（P＜0.01）。結論新診斷2型糖尿病患者在診斷初期就應重視血脂譜的篩查。
목적：탐토신진단2형당뇨병합병관심병환자혈당、혈지、당화혈홍단백（HbA1c）특점。방법선취38례신진단2형당뇨병합병관심병환자，병이37례단순신진단2형당뇨병환자，28례단순관심병환자이급37명건강대조진행연구。혈당채용포도당양화매법，혈지분석채용매법，HbA1c측정방법위리자교환고효액상색보（HPLC）법。결과신진단2형당뇨병합병관심병환자HbA1c、Lp(a)명현고우기타삼조（P＜0.01），FPG、LDL-C、TC화TG교관심병조화대조조차이유통계학의의（P＜0.01）。신진단2형당뇨병조FPG、HbA1c、TC화TG교관심병조화대조조차이유통계학의의（P＜0.01）， Lp(a)교관심병조차이유통계학의의（P＜0.01），LDL-C교대조조차이유통계학의의（P＜0.01）。관심병조년령、Lp(a)화LDL-C교대조조차이유통계학의의（P＜0.01）。결론신진단2형당뇨병환자재진단초기취응중시혈지보적사사。
Objective To investigate the clinical significance of blood glucose, blood lipid, glycosylated hemoglobin (HbA1c) in patients with newly diagnosed type 2 diabetes mellitus complicated with coronary heart disease. Methods 38 patients with newly diagnosed type 2 diabetes mellitus complicated with coronary heart disease (group A), 37 patients with type 2 diabetes mellitus (group B), 28 patients with coronary heart disease (group C) and 37 healthy controls (group D) were studied, blood glucose using glucose oxidase method, lipid analysis using enzyme method, HbA1c by ion exchange high performance liquid chromatographic method (HPLC). Results In group A, HbA1c, Lp(a) was higher than that of the other three groups (P<0.01), FPG, LDL-C, TC and TG have significant difference compared with group C and group D (P<0.01). In group B, FPG, HbA1c, TC and TG have significant difference compared with group C and group D (P<0.01), Lp(a) have significant difference compared with group C (P<0.01), LDL-C have significant difference compared with group D (P<0.01). In group C, age, Lp(a) and LDL-C have significant difference compared with group D (P<0.01). Conclusion After diagnosis, we should pay more attention early to screening blood lipid profile in the newly diagnosed type 2 diabetes patients.
