CAJ | 학술논문

目的：探讨颈动脉血管成形及支架置入术（CAS）治疗短暂性脑缺血发作（TIA）的可行性及有效性。方法：选取短暂性脑缺血发作患者43例，随机分成两组，其中CAS治疗组23例，单纯药物治疗组20例。对CAS治疗组患者施行CAS，药物治疗组患者单纯给予合适剂量的氯吡格雷、阿司匹林及阿托伐他汀治疗。对所有患者进行12个月的随访，并分别在治疗前和治疗后根据美国国立卫生院卒中量表（NIHSS）对患者的神经功能缺损评分。结果：CAS组患者施行CAS后1个月、6个月和12个月的评分与药物组患者治疗后相同时间点的评分相比，差异具有统计学意义（P＜0.05）。结论：对TIA患者施行CAS可明显改善其神经功能缺损，与单纯药物治疗相比，效果显著，且安全性高，值得在临床中广泛推广应用。
목적：탐토경동맥혈관성형급지가치입술（CAS）치료단잠성뇌결혈발작（TIA）적가행성급유효성。방법：선취단잠성뇌결혈발작환자43례，수궤분성량조，기중CAS치료조23례，단순약물치료조20례。대CAS치료조환자시행CAS，약물치료조환자단순급여합괄제량적록필격뢰、아사필림급아탁벌타정치료。대소유환자진행12개월적수방，병분별재치료전화치료후근거미국국립위생원졸중량표（NIHSS）대환자적신경공능결손평분。결과：CAS조환자시행CAS후1개월、6개월화12개월적평분여약물조환자치료후상동시간점적평분상비，차이구유통계학의의（P＜0.05）。결론：대TIA환자시행CAS가명현개선기신경공능결손，여단순약물치료상비，효과현저，차안전성고，치득재림상중엄범추엄응용。
Objective To investigate the feasibility of Carotid angioplasty and stenting (CAS)for treatment of transient ischemic attack (TIA). Methods 43 patients were randomly divided into two groups,the CAS group of 23 cases,20 cases of simple drug treat-ment group. The implementation of CAS in CAS patients in the treatment group,clopidogrel,aspirin and atorvastatin treatment group patients were treated with appropriate doses of atorvastatin treatment.For the 12 months follow-up for all patients,and respectively before treatment and after treatment,according to the National Institutes of Health Stroke America scale (NIHSS)score of neural func-tion defect of patients.Results 1 month,6 months and 12 months in group CAS underwent CAS score and drug group patients after the same time point score compared to,P<0.05 ,significant difference,with statistical significance.Conclusions The CAS implementa-tion can significantly improve the neurological function of patients with TIA,compared,and simple drug treatment effect is remarkable, and high safety,and is worthy of popularization in clinical application.