CAJ | 학술논문

目的：评价准分子激光治疗性角膜切削术（ PTK ）联合丝裂霉素c在治疗浅层角膜病变在临床上应用的效果。方法：采用PTK联合丝裂霉素c治疗10例（13只眼）角膜浅层病变，术后随访观察6～12个月并对结果进行分析。结果：术后1、3、6个月最佳矫正对数视力与术前比较，提高均数分别为0．16、0．27、0．33。13只眼术后各时间点视力均值与术前视力均值作配对t检验，差异有统计学意义。术后6个月，远视漂移度数平均为＋1．6 D ±0．21D （＋0．50D-＋3．0D）；4只眼在术后3个月，形成轻度角膜haze；所有病例未见原有角膜病变复发者。结论：PTK治疗浅层角膜病变安全有效，术后存在远视化和原有疾病可能复发等问题。
목적：평개준분자격광치료성각막절삭술（ PTK ）연합사렬매소c재치료천층각막병변재림상상응용적효과。방법：채용PTK연합사렬매소c치료10례（13지안）각막천층병변，술후수방관찰6～12개월병대결과진행분석。결과：술후1、3、6개월최가교정대수시력여술전비교，제고균수분별위0．16、0．27、0．33。13지안술후각시간점시력균치여술전시력균치작배대t검험，차이유통계학의의。술후6개월，원시표이도수평균위＋1．6 D ±0．21D （＋0．50D-＋3．0D）；4지안재술후3개월，형성경도각막haze；소유병례미견원유각막병변복발자。결론：PTK치료천층각막병변안전유효，술후존재원시화화원유질병가능복발등문제。
Objective:To evaluate the efficacy of excimer laser photot herapeutic keratectomy ( PTK) combined mitomycin C for su-perficial corneal diseases.Methods:10 cases ( 13 eyes) with superficial corneal diseases were treated with PTK combined mitomycin C . Follow up 6~12 months and the Resultswas investigated.Results:1, 3, 6 months after best corrected logarithmic compared with preopera-tive visual acuity, increase the mean of 0.16, 0.27, 0.33, respectively.13 eyes the mean postoperative visual acuity at each time point and the mean preoperative vision matching t test , the difference was statistically significant .6 months postoperatively , farsightedness drift degree average of +1.6 D ±~0.21 D (+3.0 +0.50 D);4 eyes in 3 months postoperatively , mild corneal haze;All cases did not see the original corneal disease relapses .Conclusion:PTK combined mitomycin C was safe , effective for superficial corneal diseases .But it may cause the hyperopic shi t and the possible of original diseases relapse .