CAJ | 학술논문

目的考察夫西地酸钠在4种常见输液的配伍稳定性。方法采用高效液相色谱法测定夫西地酸钠与木糖醇注射液、0.9%氯化钠注射液、5%葡萄糖注射液、10%葡萄糖注射液配伍后室温放置8h内夫西地酸钠的含量变化，以及外观、pH值的变化。结果与配伍0h比较，配伍液放置8h内外观色泽均无明显改变，pH亦变化不大，配伍液中夫西地酸的含量无明显变化。8h内夫西地酸钠含量均保持在95%以上。结论夫西地酸钠和木糖醇注射液、0.9%氯化钠注射液、5%葡萄糖注射液、10%葡萄糖注射液四种常见输液配伍后室温(25℃)放置8h内夫西地酸钠性质基本稳定。
목적고찰부서지산납재4충상견수액적배오은정성。방법채용고효액상색보법측정부서지산납여목당순주사액、0.9%록화납주사액、5%포도당주사액、10%포도당주사액배오후실온방치8h내부서지산납적함량변화，이급외관、pH치적변화。결과여배오0h비교，배오액방치8h내외관색택균무명현개변，pH역변화불대，배오액중부서지산적함량무명현변화。8h내부서지산납함량균보지재95%이상。결론부서지산납화목당순주사액、0.9%록화납주사액、5%포도당주사액、10%포도당주사액사충상견수액배오후실온(25℃)방치8h내부서지산납성질기본은정。
Objective To observe the compatible stability of Fusidic sodium for Injection with four infusions. Methods The content change of the Fusidic sodium in xylitol, 0.9% sodium chloride injection, 5% glucose injection, 10% glucose injection at dif erent time were determined by HPLC; the appearance and pH value were fol owed . Results Compared with 0h ,there were no significant changes about four mixture in appearance、pH value and content after 8 h. Conclusion The mixture of Fusidic sodium for Injection in the xylitol, 0.9% sodium chloride injection, 5% glucose injection, 10% glucose injection can be stabled within 8h under the room temperature(25℃).