CAJ | 학술논문

目的：比较脑低、高级别胶质瘤轴位的弥散张量成像（DTI）图像，分析不同级别胶质瘤DTI特点，以提高诊断准确性。方法回顾性分析泸州医学院附属医院经手术病理证实的26例低级别胶质瘤、37例高级别脑胶质瘤的轴位 T 1W/D T I图像，将瘤周神经元纤维走行分为推移、中断、神经元纤维缠结（NFT ）3种类型。结果26例低级别胶质瘤中，18例肿瘤瘤周神经元纤维出现推移，8例出现中断，无1例出现NFT ；37例高级别脑胶质瘤中9例肿瘤瘤周神经元纤维出现推移，21例出现中断，7例出现NFT ；脑低、高级别胶质瘤组间有序变量的两独立样本比较的秩和检验显示差异有统计学意义（Z＝－3．756，P＜0．05）；高级别胶质瘤出现NFT部位的χ2检验显示差异无统计学意义（P＞0．05），其中，额叶出现1例NFT ，占2．7％（1/37），颞叶出现6例NFT ，占16．2％（6/37）。结论脑低级别胶质瘤瘤周神经元纤维走行在3．0T MRI/DTI图像上多表现为推移，高级别胶质瘤多表现为中断和NFT ，高级别胶质瘤NFT多出现在颞叶、额叶。
목적：비교뇌저、고급별효질류축위적미산장량성상（DTI）도상，분석불동급별효질류DTI특점，이제고진단준학성。방법회고성분석로주의학원부속의원경수술병리증실적26례저급별효질류、37례고급별뇌효질류적축위 T 1W/D T I도상，장류주신경원섬유주행분위추이、중단、신경원섬유전결（NFT ）3충류형。결과26례저급별효질류중，18례종류류주신경원섬유출현추이，8례출현중단，무1례출현NFT ；37례고급별뇌효질류중9례종류류주신경원섬유출현추이，21례출현중단，7례출현NFT ；뇌저、고급별효질류조간유서변량적량독립양본비교적질화검험현시차이유통계학의의（Z＝－3．756，P＜0．05）；고급별효질류출현NFT부위적χ2검험현시차이무통계학의의（P＞0．05），기중，액협출현1례NFT ，점2．7％（1/37），섭협출현6례NFT ，점16．2％（6/37）。결론뇌저급별효질류류주신경원섬유주행재3．0T MRI/DTI도상상다표현위추이，고급별효질류다표현위중단화NFT ，고급별효질류NFT다출현재섭협、액협。
Objective To explore the diagnostic value of axial diffusion tensor imaging(DTI) for gliomas grading at 3 .0T MRI , analyze the characteristics of different grades gliomas of axial DTI in order to improve diagnostic accuracy .Methods A retrospec‐tive analysis was performed involving a group of 37 cases of high grade glioma and 26 cases of low grade glioma confirmed by the pathological results in affiliated hospital of Luzhou medical college ,observation analysis was obtained in axial DTI ,peritumoral neu‐rofibrillary was divided into three types :displacement ,interruption and neurofibrillary tangles(NFT) .Results among the 26 cases of low grade glioma ,there were 18 cases of displacement ;8 cases of interruption ,no NFT ;among the 37 cases of high grade glio‐mas ,there were 9 cases of displacement ,21 cases of interruption ,and 7 cases of NFT (1 case of frontal lobe ,6 cases of temporal lobe);ordinal variables rank sum test in two independent samples between high grade glioma group and low grade glioma showed significant differences(Z= -3 .756 ,P<0 .05);χ2 test showed no significant difference(P>0 .05) ,frontal lobe appeared NFT in 1 case ,accounting for 2 .7% (1/37) ,temporal lobe appeared NFT in 6 cases ,accounting for 16 .2% (6/37) .Conclusion Peritumoral neurofibrillary of the low grade gliomas more performed displacement ,the high grade gliomas show more interrupts and NFT at 3 .0T MRI ,NFT in high grade gliomas is often seen in the temporal and frontal lobe .