CAJ | 학술논문

目的：观察甘露聚糖肽注射液用于烧伤感染治疗的临床疗效。方法2009年05月～2012年07月期间在四川省南充市中心医院收治的烧伤感染患者100例，随机分为治疗组(n=50)和对照组(n=50)，均按常规治疗，治疗组患者静脉注射多抗甘露聚糖肽注射液，对照组患者皮下注射重组人生长激素。结果治疗组患者平均住院时间较对照组显著缩短（P=0.042），临床总有效率，及血IgA、IgG、IgM等免疫功能指标较对照组显著提高（P=0.037）。2组患者血蛋白质、转铁蛋白、前白蛋白、血糖、胰岛素及尿钠、钾、氯等指标比较差异无统计学意义。结论甘露聚糖肽能有效增强机体免疫功能，促进创面愈合，缩短住院时间，提高临床疗效。
목적：관찰감로취당태주사액용우소상감염치료적림상료효。방법2009년05월～2012년07월기간재사천성남충시중심의원수치적소상감염환자100례，수궤분위치료조(n=50)화대조조(n=50)，균안상규치료，치료조환자정맥주사다항감로취당태주사액，대조조환자피하주사중조인생장격소。결과치료조환자평균주원시간교대조조현저축단（P=0.042），림상총유효솔，급혈IgA、IgG、IgM등면역공능지표교대조조현저제고（P=0.037）。2조환자혈단백질、전철단백、전백단백、혈당、이도소급뇨납、갑、록등지표비교차이무통계학의의。결론감로취당태능유효증강궤체면역공능，촉진창면유합，축단주원시간，제고림상료효。
Objective To observe the clinical effect of mannatide treatment with burn infection. Methods 100 burn patients admitted to Sichuan Nanchong Central Hospital from May 2009 to July 2012 were randomly divided into control group and treatment group, each group had 50 cases. Both of two groups were given conventional treatment, treatment group were treated with intravenous mannatide,control group were injected recombinant human growth hormone. Results The average length of stay in treatment group was signiifcantly shorter than control group (P=0.042). The clinical total effective rate, serum IgA, IgG, IgM and other indicators of immune function were improved signiifcantly compared with control group (P=0.037). There was no statistical signiifcance in blood protein, transferrin, prealbumin, glucose, insulin, urinary sodium, urinary potassium, chloride and other indicators of patients between two groups. Conclusion Mannatide can effectively enhance immune function, promote wound healing, shorter hospital stay and improve the clinical efifcacy.