CAJ | 학술논문

目的：观察丹参川芎嗪注射液在辅助辨治缺血性脑卒中过程中的作用和临床效果。方法选取142例缺血性脑卒中患者，按照随机数字表分为试验组和对照组。对照组（n=71）采用常规治疗；试验组（n=71）在常规治疗的基础上加用丹参川芎嗪注射液进行辅助辨治。分别观察治疗前后2组患者的血液流变学变化、神经功能改善情况和治疗效果并进行统计学分析。结果治疗后，对照组患者血浆黏度1.91±0.35，红细胞压积(49.58±1.04)%；试验组患者血浆黏度1.17±0.28，红细胞压积(38.97±1.31)%，2组差异显著（P＜0.05）。治疗前对照组神经功能评分为22.49±1.21，试验组患者治疗前评分为23.18±1.74，2组差别不大。治疗后，对照组评分10.58±0.94，试验组为4.62±2.05，2组差异显著（P＜0.05）。对照组治疗后总有效率80.3%；试验组治疗后总有效率88.7%，2组差异显著（P＜0.05）。结论丹参川芎嗪注射液辅助辨治缺血性脑卒中疗效确切，患者症状得到有效缓解。
목적：관찰단삼천궁진주사액재보조변치결혈성뇌졸중과정중적작용화림상효과。방법선취142례결혈성뇌졸중환자，안조수궤수자표분위시험조화대조조。대조조（n=71）채용상규치료；시험조（n=71）재상규치료적기출상가용단삼천궁진주사액진행보조변치。분별관찰치료전후2조환자적혈액류변학변화、신경공능개선정황화치료효과병진행통계학분석。결과치료후，대조조환자혈장점도1.91±0.35，홍세포압적(49.58±1.04)%；시험조환자혈장점도1.17±0.28，홍세포압적(38.97±1.31)%，2조차이현저（P＜0.05）。치료전대조조신경공능평분위22.49±1.21，시험조환자치료전평분위23.18±1.74，2조차별불대。치료후，대조조평분10.58±0.94，시험조위4.62±2.05，2조차이현저（P＜0.05）。대조조치료후총유효솔80.3%；시험조치료후총유효솔88.7%，2조차이현저（P＜0.05）。결론단삼천궁진주사액보조변치결혈성뇌졸중료효학절，환자증상득도유효완해。
Objective To observe the effect of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in inauxiliary treatment of ischemic stroke and its clinical efficacy. Methods 142 cases of patients with ischemic stroke, were randomly divided into experimental group and control group. Control group(n=71) were treated with conventional therapy. Test group(n=71) were treated with Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection on the basis of conventional therapy. Hemorheological changes, nerve function improvement and treatment efifcacy in two groups before and after treatment were observed and analyzed. Results After treatment, the plasma viscosity and hematocrit in control group were 1.91±0.35, (49.58±1.04)%; while experimental group were 1.17±0.28, (38.97±1.31)%, the differences between two groups were signiifcant(P<0.05). Before treatment, the neurological function score in control group was 22.49±1.21, while experimental group was 23.18±1.74, there was no signiifcant difference between two groups. After treatment, the neurological function score in control group was 10.58±0.94, while experimental group was 4.62±2.05, the difference was signiifcant(P<0.05). The total effective rate was 80.3%in control group ,while 88.7% in experimental group, the difference was signiifcant(P<0.05). Conclusion The clinical efifcacy of Salviae Miltiorrhizae and Ligustrazine Hydrochloride Injection in auxiliary treatment of ischemic stroke was accurate, and it can alleviate the symptom of patients.