CAJ | 학술논문

目的：评估复方苦参注射液治疗恶性肿瘤癌性疼痛的临床效果。方法选取2010年2月～2013年4月间湖北省黄冈市中心医院进行治疗的恶性肿瘤患者100例为研究对象进行回顾性分析；根据随机数字表随机均分为对照组（n=50）和研究组（n=50）。在接受常规治疗的基础上，对照组加用三阶梯止痛法，研究组加用复方苦参注射液；采用疼痛数学评估法（numerical rating scale，NRS）评估2组患者治疗前后的疼痛状况并进行对比；同时用Karnofsky评分法评估2组患者治疗前后的生活质量评分并进行对比。结果研究组治疗疼痛的效果好于对照组，差异具有统计学意义（P＜0.05）；研究组生活质量评分优于对照组的，差异具有统计学意义（P＜0.05）。结论复方苦参注射液治疗恶性肿瘤癌性疼痛的临床疗效较好，且能够显著改善患者生活质量。
목적：평고복방고삼주사액치료악성종류암성동통적림상효과。방법선취2010년2월～2013년4월간호북성황강시중심의원진행치료적악성종류환자100례위연구대상진행회고성분석；근거수궤수자표수궤균분위대조조（n=50）화연구조（n=50）。재접수상규치료적기출상，대조조가용삼계제지통법，연구조가용복방고삼주사액；채용동통수학평고법（numerical rating scale，NRS）평고2조환자치료전후적동통상황병진행대비；동시용Karnofsky평분법평고2조환자치료전후적생활질량평분병진행대비。결과연구조치료동통적효과호우대조조，차이구유통계학의의（P＜0.05）；연구조생활질량평분우우대조조적，차이구유통계학의의（P＜0.05）。결론복방고삼주사액치료악성종류암성동통적림상료효교호，차능구현저개선환자생활질량。
Objective To evaluate the clinical efifcacy of Matrine injection on malignant cancer pain treatment. Methods 100 patients in Central Hospital of Huanggang from February 2010 to April 2013 were randomly divided into two groups(control group and research group) for retrospective study(n=50). Based on the conventional treatment, control group were received three-step analgesic ladder, and research group were treated with matrine injections. The pain scores and Karn of sky scores were evaluated and compared before and after treatment in each group, and were compared between two groups. Results The pain score and Karn of sky score in research group after treatment were signiifcantly better than control group(P<0.05). Conclusion Matrine injection could relief pain level and improve patients' quality of life of malignant cancer patient.