信阳师范学院学报(自然科学版)
信暘師範學院學報(自然科學版)
신양사범학원학보(자연과학판)
JOURNAL OF XINYANG NORMAL UNIVERSITY(NATURAL SCIENCE EDITION)
2014年
2期
162-166
,共5页
非线性感染率%时滞%稳定性%Hopf分支
非線性感染率%時滯%穩定性%Hopf分支
비선성감염솔%시체%은정성%Hopf분지
nonlinear infection rate%intracellular delay%stability%Hopf bifurcation
将时滞及饱和发生率引入到一类具有初级细胞毒性T淋巴细胞( CTLp)和效应细胞毒性T淋巴细胞( CTLe)免疫反应的病毒感染模型,证明了改进后模型无病毒感染平衡点及无免疫平衡点的全局渐近稳定性。同时,给出了免役应答平衡点(正平衡点)产生Hopf分支的充分条件。最后,数值模拟验证了理论结果。
將時滯及飽和髮生率引入到一類具有初級細胞毒性T淋巴細胞( CTLp)和效應細胞毒性T淋巴細胞( CTLe)免疫反應的病毒感染模型,證明瞭改進後模型無病毒感染平衡點及無免疫平衡點的全跼漸近穩定性。同時,給齣瞭免役應答平衡點(正平衡點)產生Hopf分支的充分條件。最後,數值模擬驗證瞭理論結果。
장시체급포화발생솔인입도일류구유초급세포독성T림파세포( CTLp)화효응세포독성T림파세포( CTLe)면역반응적병독감염모형,증명료개진후모형무병독감염평형점급무면역평형점적전국점근은정성。동시,급출료면역응답평형점(정평형점)산생Hopf분지적충분조건。최후,수치모의험증료이론결과。
Intracellular delay and nonlinear infection rate were introduced into a class of viral infection model with primary and secondary CTL response to viral infections. Global asymptotic stability of the infection free equilibrium and the no-immune response equilibrium were discussed. Then, the conditions for the existence of Hopf bifurcation near the positive equilibrium were given. Finally, numerical simulations verified the theoretical results.