CAJ | 학술논문

目的：探讨青年人胃癌的临床病理特点，提高对青年人胃癌的早期诊断率。方法收集经病理确诊的21例青年人（≤44岁）胃癌的病例资料，回顾性分析其临床病理特点，包括患者的性别、年龄、幽门螺杆菌感染率、临床表现、病变部位、病理大体类型、病理组织学类型、淋巴结转移率、临床分期、误诊情况等。结果21例青年人胃癌患者女性多于男性；幽门螺杆菌（Helicobacter pylori, Hp）感染率为76.2%；好发部位是胃窦；进展期胃癌18例（85.7%）；大体类型以BorrmannⅢ型最多见；病理组织学类型以低分化腺癌和黏液腺癌为主；临床分期多为Ⅲ期；81.0%的高淋巴结转移率，误诊率偏高。结论青年人胃癌的临床病理特点是女性多发，Hp感染率高，分化低，恶性程度高，淋巴结转移率高，误诊率偏高。病理检查是确诊胃癌的最可靠方法。
목적：탐토청년인위암적림상병리특점，제고대청년인위암적조기진단솔。방법수집경병리학진적21례청년인（≤44세）위암적병례자료，회고성분석기림상병리특점，포괄환자적성별、년령、유문라간균감염솔、림상표현、병변부위、병리대체류형、병리조직학류형、림파결전이솔、림상분기、오진정황등。결과21례청년인위암환자녀성다우남성；유문라간균（Helicobacter pylori, Hp）감염솔위76.2%；호발부위시위두；진전기위암18례（85.7%）；대체류형이BorrmannⅢ형최다견；병리조직학류형이저분화선암화점액선암위주；림상분기다위Ⅲ기；81.0%적고림파결전이솔，오진솔편고。결론청년인위암적림상병리특점시녀성다발，Hp감염솔고，분화저，악성정도고，림파결전이솔고，오진솔편고。병리검사시학진위암적최가고방법。
Objective To explore the clinicopathological characteristics of gastric cancer in young people so as to raise the diagno-sis. Methods A retrospective analysis was made to the clinical data of 21 young patients(≤44years old)with gastric cancer confirmed by pathological study, including sex, age, the rate of helicobacter pylori(Hp)infection, the lesion location, pathological type, histopath-ologic type, the rate of lymph node metastasis, clinical stage and misdiagnosis. Results Female were more than male in the 21 young pa-tients with gastric cancer;the Hp infection rate was 76.2%;gastric antrum was the predilenction site of gastric cancer;18 cases were at progressing stage(85.7%);Borrmann III was the main pathological type while poorly differentiated adenocarcinoma and mucinous ade-nocarcinoma were the main histopathological types;most cases were at clinical stage III;the rate of lymph node metastasis was 81.0%and misdiagnosis rate was high. Conclusions Gastric cancer in young people is of such clinicopathological characteristics as high occur-rence in female, high rate of Hp infection, poor differentiation, high malignancy, high rate of lymph node metastasis and misdiagnosis;pathological examination is the most liable in diagnosing gastric cancer.