CAJ | 학술논문

目的：探讨醒脑静注射液治疗急性缺血性脑卒中的疗效及其对炎性因子的影响。方法选取2011年2月～2013年6月普宁市人民医院收治的急性缺血性脑卒中患者60例，随机均分为2组（n=30）。对照组采用常规治疗方法，观察组在常规治疗的基础上给予醒脑静注射液治疗。比较2组患者治疗前后神经功能缺损情况、日常生活能力改善情况、治疗有效率，并比较其对相关炎性因子的影响。结果观察组患者神经功能缺损评分及日常生活能力评分与常规治疗组比较，差别有统计学意义(P＜0.05)；观察组患者治疗总有效率明显高于对照组，差别有统计学意义(P＜0.05)；观察组患者C-反应蛋白（CRP）、肿瘤坏死因子α（TNF-α）、白细胞介素-6（IL-6）显著低于对照组，差别有统计学意义(P＜0.05)。结论在常规治疗方法的基础上对急性缺血性脑卒中患者使用醒脑静注射液能够明显改善患者症状，并有效减轻炎症反应对神经系统的抑制作用，促进神经系统功能恢复，预后良好。
목적：탐토성뇌정주사액치료급성결혈성뇌졸중적료효급기대염성인자적영향。방법선취2011년2월～2013년6월보저시인민의원수치적급성결혈성뇌졸중환자60례，수궤균분위2조（n=30）。대조조채용상규치료방법，관찰조재상규치료적기출상급여성뇌정주사액치료。비교2조환자치료전후신경공능결손정황、일상생활능력개선정황、치료유효솔，병비교기대상관염성인자적영향。결과관찰조환자신경공능결손평분급일상생활능력평분여상규치료조비교，차별유통계학의의(P＜0.05)；관찰조환자치료총유효솔명현고우대조조，차별유통계학의의(P＜0.05)；관찰조환자C-반응단백（CRP）、종류배사인자α（TNF-α）、백세포개소-6（IL-6）현저저우대조조，차별유통계학의의(P＜0.05)。결론재상규치료방법적기출상대급성결혈성뇌졸중환자사용성뇌정주사액능구명현개선환자증상，병유효감경염증반응대신경계통적억제작용，촉진신경계통공능회복，예후량호。
Objective To investigate the clinical efficacy XNJI treatment of acute ischemic stroke and its effects on inflammatory factors. Methods 60 cases to the hospital with acute ischemic stroke patients treated, the patients were randomLy divided into control group and observation group, 30 cases in each. Control group with conventional treatment, observation group was given XNJI treatment on the basis of conventional therapy. Neurological deficit situation, the ability to improve the daily lives of patients was compared before and after treatment, treatment efficiency, and compares their effects on inflammatory factors associated. Results The patients with neurological function and activities of daily living score compared with the conventional treatment group , the difference was statistically significant (P<0.05);Treatment of patients in the observation group was significantly higher total efficiency (P<0.05);patients with C-reactive protein in the observation group (CRP), tumor necrosis factor-α(TNF-α), interleukin-6 (IL-6) was significantly lower than the control group (P<0.05). Conclusion XNJI the basis of conventional treatments on patients with acute ischemic stroke can significantly improve symptoms, and effectively reduce inflammation inhibitory effect on the nervous system, the nervous system to promote functional recovery, the prognosis is good.