当代医学
噹代醫學
당대의학
CHINA CONTEMPORARY MEDICINE
2014年
14期
131-132
,共2页
巴曲酶联合依达拉奉%急性脑梗死%临床疗效%安全性
巴麯酶聯閤依達拉奉%急性腦梗死%臨床療效%安全性
파곡매연합의체랍봉%급성뇌경사%림상료효%안전성
Batroxobin edaravone%Acute cerebral infarction%Clinical efficacy%Safety
目的：探讨巴曲酶联合依达拉奉治疗急性脑梗死的临床疗效，并评估其安全性。方法选取2010年1月～2013年12月普宁市人民医院收治的急性脑梗死患者60例，采取随机双盲的方法将患者均分2组（n=30）。常规治疗组给予脱水剂、脑细胞保护类药物，全程监控血压、血糖，纠正水电解质紊乱并维持酸碱平衡状态等急性脑梗死常规治疗方法；联合治疗组在常规治疗的基础上给予巴曲酶联合依达拉奉静脉滴注治疗。比较2组患者治疗前后神经功能缺损情况、日常生活能力改善情况及治疗有效率。结果联合治疗组患者神经功能缺损评分及日常生活能力评分与常规治疗组比较，差异有统计学意义(P＜0.05)；联合治疗组患者治疗总有效率明显高于常规治疗组，差异有统计学意义(P＜0.05)。结论巴曲酶联合依达拉奉治疗急性脑梗死取得了较好的临床效果，能够显著改善患者神经功能缺损症状，提高日常生活能力，并无明显不良反应出现，值得临床推广应用。
目的：探討巴麯酶聯閤依達拉奉治療急性腦梗死的臨床療效，併評估其安全性。方法選取2010年1月～2013年12月普寧市人民醫院收治的急性腦梗死患者60例，採取隨機雙盲的方法將患者均分2組（n=30）。常規治療組給予脫水劑、腦細胞保護類藥物，全程鑑控血壓、血糖，糾正水電解質紊亂併維持痠堿平衡狀態等急性腦梗死常規治療方法；聯閤治療組在常規治療的基礎上給予巴麯酶聯閤依達拉奉靜脈滴註治療。比較2組患者治療前後神經功能缺損情況、日常生活能力改善情況及治療有效率。結果聯閤治療組患者神經功能缺損評分及日常生活能力評分與常規治療組比較，差異有統計學意義(P＜0.05)；聯閤治療組患者治療總有效率明顯高于常規治療組，差異有統計學意義(P＜0.05)。結論巴麯酶聯閤依達拉奉治療急性腦梗死取得瞭較好的臨床效果，能夠顯著改善患者神經功能缺損癥狀，提高日常生活能力，併無明顯不良反應齣現，值得臨床推廣應用。
목적：탐토파곡매연합의체랍봉치료급성뇌경사적림상료효，병평고기안전성。방법선취2010년1월～2013년12월보저시인민의원수치적급성뇌경사환자60례，채취수궤쌍맹적방법장환자균분2조（n=30）。상규치료조급여탈수제、뇌세포보호류약물，전정감공혈압、혈당，규정수전해질문란병유지산감평형상태등급성뇌경사상규치료방법；연합치료조재상규치료적기출상급여파곡매연합의체랍봉정맥적주치료。비교2조환자치료전후신경공능결손정황、일상생활능력개선정황급치료유효솔。결과연합치료조환자신경공능결손평분급일상생활능력평분여상규치료조비교，차이유통계학의의(P＜0.05)；연합치료조환자치료총유효솔명현고우상규치료조，차이유통계학의의(P＜0.05)。결론파곡매연합의체랍봉치료급성뇌경사취득료교호적림상효과，능구현저개선환자신경공능결손증상，제고일상생활능력，병무명현불량반응출현，치득림상추엄응용。
Objective To investigate batroxobin edaravone treatment of acute cerebral infarction clinical efficacy and safety evaluation of its use, it is desirable to provide a basis for clinical use. Methods 60 patients with acute cerebral infarction in our hospital, randomized, double-blind approach would take the average score of patients treated with conventional combination therapy group (n=30). Conventional treatment group was given a dehydrating agent to protect brain cells drugs, full control of blood pressure, blood sugar, and maintain correct water and electrolyte imbalance, such as acid-base balance of conventional treatment of acute cerebral infarction . Combination therapy group were given batroxobin edaravone infusion therapy based on conventional therapy. Neurological deficit situations, the ability to improve the daily lives of patients were compared before and after treatment and the treatment efficiency. Results The patients treated with neurological deficit scores and ADL score compared with the conventional treatment group were significantly different, the difference was statistically significant (P<0.05);Treatment of patients with combined treatment group was significantly higher than conventional therapy group (P<0.05). Conclusion Batroxobin edaravone treatment of acute cerebral infarction achieved good clinical results, can significantly improve symptoms in patients with neurological deficit , improving activities of daily living, there is no significant adverse reactions , worthy of clinical application.
