CAJ | 학술논문

目的：茵柴降脂汤对非酒精性脂肪性肝病（ nonalcoholic fatty liver disease ，NAFLD）患者的临床疗效观察。方法全部92例符合诊断标准的患者被随机分为治疗组和对照组，治疗组采用茵柴降脂汤治疗，对照组采用口服多烯磷脂酰胆碱胶囊治疗；以1个月为1个疗程，3个疗程结束后进行疗效统计分析。结果治疗后，两组患者的丙氨酸转氨酶（ ALT）、三酰甘油（ TG）指标、肝／脾CT值都有显著改善，且各组前后结果对比差异均有统计学意义（ P＜0．05）。治疗后两组差异无统计学意义（P＞0．05），但治疗组的体质量指数（BMI）值改善优于对照组，治疗前后比较，差异有统计学意义（P＜0．05）。结论茵柴降脂汤在降低NAFLD患者血清中ALT、TG指标，提高患者肝／脾CT值方面与常规药物多烯磷脂酰胆碱胶囊效果相当，在降低BMI值方面效果优于多烯磷脂酰胆碱胶囊。
목적：인시강지탕대비주정성지방성간병（ nonalcoholic fatty liver disease ，NAFLD）환자적림상료효관찰。방법전부92례부합진단표준적환자피수궤분위치료조화대조조，치료조채용인시강지탕치료，대조조채용구복다희린지선담감효낭치료；이1개월위1개료정，3개료정결속후진행료효통계분석。결과치료후，량조환자적병안산전안매（ ALT）、삼선감유（ TG）지표、간／비CT치도유현저개선，차각조전후결과대비차이균유통계학의의（ P＜0．05）。치료후량조차이무통계학의의（P＞0．05），단치료조적체질량지수（BMI）치개선우우대조조，치료전후비교，차이유통계학의의（P＜0．05）。결론인시강지탕재강저NAFLD환자혈청중ALT、TG지표，제고환자간／비CT치방면여상규약물다희린지선담감효낭효과상당，재강저BMI치방면효과우우다희린지선담감효낭。
Objective The clinical observation about Yin Chai Jiang Zhi Tang decoction on patients with nonalcoholic fatty liver disease .Methods All 92 patients were randomly divided into treatment group and control group ,the treatment group received Yin Chai Jiang Zhi Tang treatment .The control group received oral polyene phosphatidylcholine capsule treatment .And ask the patient to control their weight during treatment ,increase physical activity ,proper diet .In a month of a course of treatment ,the efficacy of the statis-tical analysis conducted after three courses .Results After treatment,both groups of patients with ALT ,TG index,liver/spleen CT val-ues were significantly improved,and the differences were statistically significant results were compared (P<0.05) before and after each group.After treatment,the two groups showed no significant difference (P>0.05),but BMI values to improve the treatment group than the control group,there was significant difference before and after comparison (P<0.05).Conclusion Yin Chai Jiang Zhi Tang can reduce ALT,TG in serum,and improve liver/spleen CT values respects with conventional drugs polyene phosphatidylcholine capsule quite effective in terms of reducing the effect of BMI values than conventional drugs polyene phosphatidyl choline capsules .