CAJ | 학술논문

目的：探讨脑梗死发病的危险因素及生化指标特征。方法采用回顾性调查方法，将调查对象分为脑梗死组（165例）与对照组（66例），通过Logistic回归分析、t检验方法对数据进行处理。结果单因素Logistic回归分析中，年龄、吸烟史、高血压史、糖尿病史与脑梗死发病密切相关（P＜0.05）；组间比较t检验分析中，急性期脑梗死组白细胞计数高于非急性期组对照组（P＜0.05），脑梗死患者中性粒细胞百分比、C反应蛋白、转脂蛋白a、总胆固醇、低密度脂蛋白胆固醇、血糖均高于对照组（ P＜0.05）。结论血脂、血糖、血压异常增高及吸烟是导致发病的确切危险因素，脑梗死病变初期伴明显的炎性反应，倡导健康的饮食、生活习惯及对血压、血糖、血脂的管理有助于预防脑梗死的发病，脑梗死发病初期需积极抑制炎性反应。
목적：탐토뇌경사발병적위험인소급생화지표특정。방법채용회고성조사방법，장조사대상분위뇌경사조（165례）여대조조（66례），통과Logistic회귀분석、t검험방법대수거진행처리。결과단인소Logistic회귀분석중，년령、흡연사、고혈압사、당뇨병사여뇌경사발병밀절상관（P＜0.05）；조간비교t검험분석중，급성기뇌경사조백세포계수고우비급성기조대조조（P＜0.05），뇌경사환자중성립세포백분비、C반응단백、전지단백a、총담고순、저밀도지단백담고순、혈당균고우대조조（ P＜0.05）。결론혈지、혈당、혈압이상증고급흡연시도치발병적학절위험인소，뇌경사병변초기반명현적염성반응，창도건강적음식、생활습관급대혈압、혈당、혈지적관리유조우예방뇌경사적발병，뇌경사발병초기수적겁억제염성반응。
Objective To explore risk factors ,biochemical indicators of cerebral infarction .Methods A retrospective analy-sis including 165 patients with cerebral infarction divided into acute group and non-acute group and 66 control subjects were carried out.The descriptive statistics,t test were used in the study of biochemical indicators of cerebral infarction ,logistic regression analysis were used in the study for comparing the risk factors .Results According to the results of single-factor logistic regression analysis ,sex, age,smoking history,hypertension history,diabetes were closely correlated with the occurrence of cerebral infarction (P<0.05).Ac-cording to the results of t test ,the WBC of patients with cerebral infarction in acute group was significant higher than WBC of patients in non-acute group and control group (P<0.05).The percentage of GRAN,and levels of CRP,LPA,TC,LDL-C and GLU of patients with cerebral infarction were significant higher than that of patients in the control group (P<0.05).Conclusion Abnormal blood lipids, increased blood glucose level ,increased blood pressure and the smoking were confirmed risk factors of cerebral infarction ,the inflamma-tory reaction during initial stage of cerebral infarction ,reasonable diet ,healthy life style as well as the good management of the underly-ing disease were significant measures for prevention of cerebral infarction .On the early stage of cerebral infarction should inhibit the in-flammatory reaction .