中华胃肠外科杂志
中華胃腸外科雜誌
중화위장외과잡지
CHINESE JOURNAL OF GASTROINTESTINAL SURGERY
2014年
5期
516-520
,共5页
急性肠系膜上静脉血栓%进阶式诊治%损伤控制外科%介入治疗
急性腸繫膜上靜脈血栓%進階式診治%損傷控製外科%介入治療
급성장계막상정맥혈전%진계식진치%손상공제외과%개입치료
Acute superior mesenteric venous thrombosis%Step-up modality of diagnosis and treatment%Damage control surgery%Interventional therapy
急性肠系膜上静脉血栓(ASMVT)是一种少见的胃肠道缺血性疾病。随着血管增强CT、血管造影以及腹腔镜探查等诊断技术的不断进步,其发病率不断提高,更多患者能够获得早期诊断。抗凝、介入技术以及损伤控制性手术的综合应用不断提升着临床疗效。当前,诊断技术主要为血管增强CT,同时以血管造影对血栓范围及程度进行评估,必要时行腹腔镜直接评估肠道缺血情况;治疗则以全身抗凝为基石,局部介入导管抗凝和溶栓使血管再通为主要治疗核心,辅以肠系膜动脉解痉及多种腔内操作治疗,必要时行坏死肠管手术切除加两端造口或腹腔开放等损伤控制性手术;形成ASMVT进阶式诊治模式,有望能进一步提高临床整体疗效。本文将该治疗模式的最新研究进展作一综述。
急性腸繫膜上靜脈血栓(ASMVT)是一種少見的胃腸道缺血性疾病。隨著血管增彊CT、血管造影以及腹腔鏡探查等診斷技術的不斷進步,其髮病率不斷提高,更多患者能夠穫得早期診斷。抗凝、介入技術以及損傷控製性手術的綜閤應用不斷提升著臨床療效。噹前,診斷技術主要為血管增彊CT,同時以血管造影對血栓範圍及程度進行評估,必要時行腹腔鏡直接評估腸道缺血情況;治療則以全身抗凝為基石,跼部介入導管抗凝和溶栓使血管再通為主要治療覈心,輔以腸繫膜動脈解痙及多種腔內操作治療,必要時行壞死腸管手術切除加兩耑造口或腹腔開放等損傷控製性手術;形成ASMVT進階式診治模式,有望能進一步提高臨床整體療效。本文將該治療模式的最新研究進展作一綜述。
급성장계막상정맥혈전(ASMVT)시일충소견적위장도결혈성질병。수착혈관증강CT、혈관조영이급복강경탐사등진단기술적불단진보,기발병솔불단제고,경다환자능구획득조기진단。항응、개입기술이급손상공제성수술적종합응용불단제승착림상료효。당전,진단기술주요위혈관증강CT,동시이혈관조영대혈전범위급정도진행평고,필요시행복강경직접평고장도결혈정황;치료칙이전신항응위기석,국부개입도관항응화용전사혈관재통위주요치료핵심,보이장계막동맥해경급다충강내조작치료,필요시행배사장관수술절제가량단조구혹복강개방등손상공제성수술;형성ASMVT진계식진치모식,유망능진일보제고림상정체료효。본문장해치료모식적최신연구진전작일종술。
Acute superior mesenteric venous thrombosis is rare. With advance in CT venography, angiography and diagnostic laparoscopy, the incidence of acute superior mesenteric venous thrombosis has increased worldwide with more access to early diagnosis. The use of anticoagulatory medication, interventional radiology, and damage control approach has resulted in better clinical outcomes. At present, the new step-up approach for acute superior mesenteric venous thrombosis includes CT venography as the main diagnostic technique, anticoagulation as the cornerstone of therapy, local transcatheter thrombolytic therapy as the key recanalization method, and adjunctive use of arterial spasmolysis and various endovascular manipulation and damage control surgery by intestinal resection plus jejunostomy and ileostomy or open abdomen. This strategy may further improve clinical outcomes. This review will present the most recent advance in this strategy.