CAJ | 학술논문

为了了解有不良孕产史夫妇的染色体断裂率的发生情况，笔者对来河南省人口和计划生育科学技术研究院就诊的有不良孕产史夫妇的染色体断裂率分析的检查结果进行统计学分析。分析结果显示：男性患者的就诊年龄平均为29.07岁，女性患者的就诊年龄平均为28.15岁，年龄与染色体检测结果间无相关。男性患者中未发现断裂的占男性总数的32.38%，女性患者中未发现染色体断裂的占女性总数的37.7%；男性染色体断裂率为1的占男性总数的38.11%，女性染色体断裂率为1的占女性总数的34.43%；男性染色体断裂率为2的占男性总数的21.72%，女性染色体断裂率为2的占女性总数的23.36%；男性染色体断裂率为3的占男性总数的7.79%，女性染色体断裂率为3的占女性总数的2.87%；女性染色体断裂率为4的占女性总数的0.82%；女性染色体断裂率为6的占女性总数的0.41%；女性染色体断裂率为9的占女性总数的0.41%。男性患者的染色体断裂率均值无差别（P>0.05）。男、女患者的染色体断裂率均值在1.01，患者平均年龄为29.53岁，经检查有染色体断裂占64.96%。通过研究发现，染色体断裂率增高可能是引起夫妇中发生胎停、流产、胎儿发育不良等不良孕产现象的重要原因之一。
위료료해유불량잉산사부부적염색체단렬솔적발생정황，필자대래하남성인구화계화생육과학기술연구원취진적유불량잉산사부부적염색체단렬솔분석적검사결과진행통계학분석。분석결과현시：남성환자적취진년령평균위29.07세，녀성환자적취진년령평균위28.15세，년령여염색체검측결과간무상관。남성환자중미발현단렬적점남성총수적32.38%，녀성환자중미발현염색체단렬적점녀성총수적37.7%；남성염색체단렬솔위1적점남성총수적38.11%，녀성염색체단렬솔위1적점녀성총수적34.43%；남성염색체단렬솔위2적점남성총수적21.72%，녀성염색체단렬솔위2적점녀성총수적23.36%；남성염색체단렬솔위3적점남성총수적7.79%，녀성염색체단렬솔위3적점녀성총수적2.87%；녀성염색체단렬솔위4적점녀성총수적0.82%；녀성염색체단렬솔위6적점녀성총수적0.41%；녀성염색체단렬솔위9적점녀성총수적0.41%。남성환자적염색체단렬솔균치무차별（P>0.05）。남、녀환자적염색체단렬솔균치재1.01，환자평균년령위29.53세，경검사유염색체단렬점64.96%。통과연구발현，염색체단렬솔증고가능시인기부부중발생태정、유산、태인발육불량등불량잉산현상적중요원인지일。
To understand the incidence of chromosome breakage rates for the adverse preg-nancy history in the infertility couples,we analyzed statistically the chromosomal breakage rates in the infertility couples which have adverse pregnancy history. The results show that:The male patients average age was 29.07,the female patients average age was 28.15,their age and chromosome breakage showed no correlation. The male patients have founded no breakage accounted for 32.38 % of the total in the male patients,the female patients found no chromo-some breakage accounted for 37.7%of the total number of females patients;they have 1%of breakage rates accounted for 38.11%of the total in the male cases and the female patients were 34.43%;they have 2%of breakage rates which accounted for 21.72%in total male cases and the female were 23.36 %;they have 3 % of chromosome breakage rates which accounted for 7.79%in the male cases and the female were 2.87%;they have 4%,6%and 9%of the chro-mosome breakage rates that accounted respectively for 0.82%,0.41%,0.41%in total female. The chromosomal breakage rates in the male patients and female no difference (P>0.05). The average chromosome breakage rates were 1.01,their average age was 29.53 and the chro-mosome breakage rates were 64.96 % in the total cases. The increased rates of chromosomal breakage may be one of the important reasons for embryo damage、miscarriage and other the ad-verse pregnancy in the infertility couples.