CAJ | 학술논문

目的：分析和总结阴沟肠杆菌肺炎的临床特点和其对抗菌药物的敏感性的分布情况。方法对51例阴沟肠杆菌肺炎的临床资料进行统计分析，测定该菌的药物敏感性。结果阴沟肠杆菌肺炎多见于65岁以上老年患者（76.47%），其中多存在于低蛋白血症患者（60.78%）和患有基础疾病患者，如慢性阻塞性肺病（21.57%）、脑血管意外（27.45%）和糖尿病（33.33%）等。临床科室主要分布于老年科13例、外科7例和呼吸科6例，临床表现主要为咳嗽、咳痰51例（100%）。胸部X线均呈现程度不等的肺部浸润阴影。药敏检测表明，哌拉西林/他唑巴坦、头孢哌酮/舒巴坦、美罗培南、帕尼培南、亚胺培南/西司他丁、阿米卡星、庆大霉素、妥布霉素比较敏感外（100%～66.67%），该菌广泛耐药。结论阴沟肠杆菌肺炎好发于老年、有基础疾病及免疫功能低下者，及早进行细菌药敏检测和选择可能敏感的抗菌药物可改善预后。
목적：분석화총결음구장간균폐염적림상특점화기대항균약물적민감성적분포정황。방법대51례음구장간균폐염적림상자료진행통계분석，측정해균적약물민감성。결과음구장간균폐염다견우65세이상노년환자（76.47%），기중다존재우저단백혈증환자（60.78%）화환유기출질병환자，여만성조새성폐병（21.57%）、뇌혈관의외（27.45%）화당뇨병（33.33%）등。림상과실주요분포우노년과13례、외과7례화호흡과6례，림상표현주요위해수、해담51례（100%）。흉부X선균정현정도불등적폐부침윤음영。약민검측표명，고랍서림/타서파탄、두포고동/서파탄、미라배남、파니배남、아알배남/서사타정、아미잡성、경대매소、타포매소비교민감외（100%～66.67%），해균엄범내약。결론음구장간균폐염호발우노년、유기출질병급면역공능저하자，급조진행세균약민검측화선택가능민감적항균약물가개선예후。
Objective To analyze and summarize the clinical features and distribution of antibiotic susceptibility of Enterobacter cloacae pneumonia. Methods We statistically analyzed the clinical data of fifty-one cases of Enterobacter cloacae and determined drug susceptibility of this bactiria.Results 39 out of 51(76.47%)patients were elderly.100%patients were with underlying disease, while 11(21.57%)cases had chronic obstructive pulmonary disease history, 31(60.78%)cases were with hypoproteinaemia. Chest X-ray showed different-degree shadow on lungs. Besides panipenem、Imipenem and Cilastatin、cefoperazone and sulbactam、Amikacin、Piperacillin/tazo、Gentamicin、Meropenem、Tobramycin were susceptive(100~66.67%), the drug susceptibility test showed,this bactiria were resistant to lots of antibiotics. Conclusion The risk factors of Enterobacter cloacae pneumonia were ageing, underlying diseases and immunodeficiency. Early drug sensitivity test and choosing susceptive antibiotics would improve the prognosis.