CAJ | 학술논문

脑出血是常见的出血性卒中，具有较高的致残率与病死率。目前关于脑出血后脑损伤的机制逐渐明了，脑出血后红细胞开始裂解并释放出铁离子，后者通过氧化应激反应引起脑损伤。大量的动物实验证明铁鳌合剂去铁胺能够减轻脑出血后的神经损伤，本文主要就去铁胺治疗脑出血后脑水肿的研究加以综述。
뇌출혈시상견적출혈성졸중，구유교고적치잔솔여병사솔。목전관우뇌출혈후뇌손상적궤제축점명료，뇌출혈후홍세포개시렬해병석방출철리자，후자통과양화응격반응인기뇌손상。대량적동물실험증명철오합제거철알능구감경뇌출혈후적신경손상，본문주요취거철알치료뇌출혈후뇌수종적연구가이종술。
Intracerebral hemorrhage is one of common diseases in neurology, and with high morbidity and mortality. Currently the mechanism of the brain injury of intracerebral hemorrhage is clear gradually. When the intracerebral hemorrhage occurrs, the lysis of erythrocyte begins and iron ions are released. Iron ions caused brain damage through oxidative stress response. A large number of animal experiments have shown that iron chelator deferoxamine can reduce neurological damage after intracerebral hemorrhage. We reviewed the progress of the treatment of the cerebral edema after intracerebral hemorrhage with deferoxamine.