岭南现代临床外科
嶺南現代臨床外科
령남현대림상외과
LINGNAN MODERN CLINICS IN SURGERY
2014年
3期
281-283
,共3页
生长激素腺瘤%生长激素%胰岛素类生长因子1%糖尿病%高血压
生長激素腺瘤%生長激素%胰島素類生長因子1%糖尿病%高血壓
생장격소선류%생장격소%이도소류생장인자1%당뇨병%고혈압
Growth hormone-secreting adenomas%Growth hormone%Insulin like growth factor I (IGF-I)%Diabetes%Hypertension
目的:探讨垂体生长激素腺瘤病人经蝶窦显微术后IGF-I水平与高血压、糖尿病等并发症的关系。方法回顾性调查经蝶窦手术治疗资料完整的73例垂体生长激素腺瘤患者的临床资料,其中伴有糖尿病21例,高血压15例,按术后IGF-I水平治愈标准评价手术疗效,分析IGF-I水平与高血压、糖尿病的关系。结果15例IGF-I水平正常者中有11例糖尿病症状缓解,6例IGF-I水平未恢复正常者中有1例糖尿病症状缓解(P<0.05);10例IGF-I水平正常者中有6例高血压症状缓解,5例IGF-I水平未恢复正常者中有1例高血压症状缓解。结论垂体生长激素腺瘤术后IGF-I水平恢复正常,能改善肢端肥大症病人糖尿病、高血压的临床症状。
目的:探討垂體生長激素腺瘤病人經蝶竇顯微術後IGF-I水平與高血壓、糖尿病等併髮癥的關繫。方法迴顧性調查經蝶竇手術治療資料完整的73例垂體生長激素腺瘤患者的臨床資料,其中伴有糖尿病21例,高血壓15例,按術後IGF-I水平治愈標準評價手術療效,分析IGF-I水平與高血壓、糖尿病的關繫。結果15例IGF-I水平正常者中有11例糖尿病癥狀緩解,6例IGF-I水平未恢複正常者中有1例糖尿病癥狀緩解(P<0.05);10例IGF-I水平正常者中有6例高血壓癥狀緩解,5例IGF-I水平未恢複正常者中有1例高血壓癥狀緩解。結論垂體生長激素腺瘤術後IGF-I水平恢複正常,能改善肢耑肥大癥病人糖尿病、高血壓的臨床癥狀。
목적:탐토수체생장격소선류병인경접두현미술후IGF-I수평여고혈압、당뇨병등병발증적관계。방법회고성조사경접두수술치료자료완정적73례수체생장격소선류환자적림상자료,기중반유당뇨병21례,고혈압15례,안술후IGF-I수평치유표준평개수술료효,분석IGF-I수평여고혈압、당뇨병적관계。결과15례IGF-I수평정상자중유11례당뇨병증상완해,6례IGF-I수평미회복정상자중유1례당뇨병증상완해(P<0.05);10례IGF-I수평정상자중유6례고혈압증상완해,5례IGF-I수평미회복정상자중유1례고혈압증상완해。결론수체생장격소선류술후IGF-I수평회복정상,능개선지단비대증병인당뇨병、고혈압적림상증상。
Objective To evaluate the relationship of postoperative Insulin-like growth factor I (IGF-I).level with diabetes and hypertensions for growth hormone (GH)-secreting adenoma patients after transsphenoidal microsurgery. Methods Seventy-three patients harboring GH-secreting adenomas underwent transsphenoidal microsurgery were investigated retrospectively. .Biochemical remission was defined as a normal age- and gender-matched IGF-I level. Among them , 21 cases were diabetes and 15 cases were hypertensions..Results Eleven cases got clinical symptomatic relief in diabetes among 15 cases with normal IGF-I level,and one case was clinical symptomatic relief among 6 cases with abnormal IGF-I level (P<0.05)..Six cases were hypertension clinical symptomatic relief among 10 cases with normal IGF-I level,.and one case was hypertension clinical symptomatic relief among 5 cases with abnormal IGF-I level..Conclusion Normal postoperative IGF-I level could moderate diabetes and hyperten-sion clinical symptoms for acromegalic patients with GH-secreting adenomas.