CAJ | 학술논문

目的：观察低T3综合征（ LT3S）在急性前壁心肌梗死患者中的发病情况，探讨其对患者远期预后的影响。方法对住院治疗的急性前壁心肌梗死121例患者行甲状腺功能检测和心脏超声等检查，并根据甲状腺功能情况进行分组；统计随诊期间不良事件发生率（包括再梗、心力衰竭、恶性心律失常及心源性死亡），分析相关影响因素。结果121例急性前壁心肌梗死患者中51例（42．15％）伴低T3综合征。血清游离三碘甲状腺原氨酸（FT3）水平是远期预后的独立危险因素；低FT3与死亡率明显相关。出院患者平均随访（20．5±7．8）月，Cox模型分析显示，FT3水平是累积死亡风险首要预测因子（HR 5．17，95％CI：2．57～8．69），其次是年龄和左室射血分数。结论急性前壁心肌梗死合并低T3综合征对预测患者病情严重程度和远期预后有重要价值。
목적：관찰저T3종합정（ LT3S）재급성전벽심기경사환자중적발병정황，탐토기대환자원기예후적영향。방법대주원치료적급성전벽심기경사121례환자행갑상선공능검측화심장초성등검사，병근거갑상선공능정황진행분조；통계수진기간불량사건발생솔（포괄재경、심력쇠갈、악성심률실상급심원성사망），분석상관영향인소。결과121례급성전벽심기경사환자중51례（42．15％）반저T3종합정。혈청유리삼전갑상선원안산（FT3）수평시원기예후적독립위험인소；저FT3여사망솔명현상관。출원환자평균수방（20．5±7．8）월，Cox모형분석현시，FT3수평시루적사망풍험수요예측인자（HR 5．17，95％CI：2．57～8．69），기차시년령화좌실사혈분수。결론급성전벽심기경사합병저T3종합정대예측환자병정엄중정도화원기예후유중요개치。
Objective To observe the prevalence of low T 3 syndrome ( LT3S) in patients with acute anterior myocardial in-farction and study its impact on the long -term prognosis .Methods Totally 121 patients with acute anterior myocardial in-farction received thyroid function tests and cardiac ultrasound examination .They were grouped according to the thyroid hor-mone profile.Statistical analysis of adverse outcomes during follow -up (including re-infarction, heart failure, malignant arrhythmias and cardiac death ) were performed to correlate with the related factors .Results Among the 121 patients with a-cute anterior myocardial infarction , 51 cases (42.15%) had low T3 syndrome.Free triiodothyronine (FT3) level was an independent risk factor for long -term prognosis;low FT3 was significantly associated with mortality .The average time of patients discharged from hospital during follow -up was (20.5 ±7.8) months.Cox regression analysis showed that FT 3 level was the primary predictor of the cumulative risk of death (HR 5.17, 95%CI:2.57-8.69), followed by age and left ventricular ejection fraction .Conclusion The recognition of patients complicated with low T 3 syndrome and acute anterior myocardial infarction plays an important role in predicting the disease severity and long -term outcomes .