CAJ | 학술논문

【目的】探讨改良拮抗剂方案促排卵治疗后冻融胚胎移植的临床结局是否优于新鲜胚胎移植。【方法】回顾性分析本中心2012年6～9月采用改良拮抗剂方案促排卵后将全胚冷冻后再行冻融胚胎移植的患者（冻胚组，68例）与当周期行新胚移植（鲜胚组，82例）的临床结局。【结果】冻胚组胚胎着床率、临床妊娠率分别为43．38％、66．17％，较鲜胚组胚胎着床率（30．98％）、临床妊娠率（42．68％）明显升高（ P＜0．05），而其流产率（8．89％ vs 11．43％）和多胎妊娠率（31．1％ vs 34．3％）比较差异均无显著性（均P＞0．05）。【结论】改良拮抗剂方案促排卵治疗中将全胚冷冻保存后再行冻融胚胎移植可以大大地提高临床妊娠率。
【목적】탐토개량길항제방안촉배란치료후동융배태이식적림상결국시부우우신선배태이식。【방법】회고성분석본중심2012년6～9월채용개량길항제방안촉배란후장전배냉동후재행동융배태이식적환자（동배조，68례）여당주기행신배이식（선배조，82례）적림상결국。【결과】동배조배태착상솔、림상임신솔분별위43．38％、66．17％，교선배조배태착상솔（30．98％）、림상임신솔（42．68％）명현승고（ P＜0．05），이기유산솔（8．89％ vs 11．43％）화다태임신솔（31．1％ vs 34．3％）비교차이균무현저성（균P＞0．05）。【결론】개량길항제방안촉배란치료중장전배냉동보존후재행동융배태이식가이대대지제고림상임신솔。
[Objective]To explore whether clinical outcome of frozen-thawed embryo transfer after the improved pro-tocol of antagonist for ovarian stimulation is better than that of fresh embryo transfer .[Methods]Clinical outcomes of 68 patients undergoing frozen-thawed embryo transfer following total embryo cryopreservation after the improved protocol of antagonist for ovarian stimulation (frozen-thawed embryo group ) and 82 concurrent patients undergoing fresh embryo transfer(fresh embryo group) in our center from June 2012 to Sept .2012 were analyzed retrospectively .[Results] The implantation rate and clinical pregnancy rate in frozen-thawed embryo group were 43 .38% and 66 .17% respectively , which were obviously higher than those in fresh embryo group (30 .98% and 42 .68% ,respectively)( P <0 .05) .There was no significant difference in the abortion rate (8 .89% vs .11 .43% ) and multiple pregnancy rate(31 .1% vs .34 .3% ) between two groups(all P>0 .05) .[Conclusion] Frozen-thawed embryo transfer following total embryo cryopreservation in the improved protocol of antagonist for ovarian stimulation can greatly improve the clinical pregnancy rate .