中国小儿急救医学
中國小兒急救醫學
중국소인급구의학
CHINESE PEDIATRIC EMERGENCY MEDICINE
2014年
5期
316-318
,共3页
FEAST实验%液体复苏%脓毒症%脓毒症休克%儿童
FEAST實驗%液體複囌%膿毒癥%膿毒癥休剋%兒童
FEAST실험%액체복소%농독증%농독증휴극%인동
FEAST trial%Fluid resuscitation%Sepsis%Septic shock%Children
及时识别和治疗儿童脓毒性休克是改善预后,降低病死率的关键.然而,目前仍缺乏儿童脓毒症液体复苏的统一认识.最近关于发热和灌注不足儿童的大量液体复苏的支持疗法研究结果更是引发人们对儿童液体复苏容量治疗的激烈讨论.该文就大量液体复苏的支持疗法的现状和可能机制进行分析.
及時識彆和治療兒童膿毒性休剋是改善預後,降低病死率的關鍵.然而,目前仍缺乏兒童膿毒癥液體複囌的統一認識.最近關于髮熱和灌註不足兒童的大量液體複囌的支持療法研究結果更是引髮人們對兒童液體複囌容量治療的激烈討論.該文就大量液體複囌的支持療法的現狀和可能機製進行分析.
급시식별화치료인동농독성휴극시개선예후,강저병사솔적관건.연이,목전잉결핍인동농독증액체복소적통일인식.최근관우발열화관주불족인동적대량액체복소적지지요법연구결과경시인발인문대인동액체복소용량치료적격렬토론.해문취대량액체복소적지지요법적현상화가능궤제진행분석.
Early recognition and treatment of pediatric septic shock is key strategy to improve prognosis and reduce the mortality,yet controversy still surrounds the current fluid therapy approach.Recently,the results of the Fluid Expansion as Supportive Therapy (FEAST) trial in African children with severe febrile and hypoperfusion illnesses challenge many established principles about pediatric fluid resuscitation,and lead to intense discussion.This review is to describe the current fluid supportive therapy and possible potential mechanisms of increased death associated with bolus resuscitation.