CAJ | 학술논문

目的：体外实验比较氟离子导入与氟化泡沫对人工根面龋再矿化作用的差异，探讨氟离子导入的作用机制。方法：制备人工早期根面龋模型35个，随机分为5组：空白对照组、1．23％氟化泡沫组、氟离子导入组、氟化钠溶液组及生理盐水导入组。各组样本经过pH循环处理后，于扫描电镜和激光共聚焦显微镜下拍摄图像，并分析结果。结果：氟离子导入组及氟化泡沫组样品表面较其余各组光滑，可见明显的再矿化沉积物；二者脱矿深度与荧光面积相对于其余各组显著减小（P＜0．01），但两组间无显著差异（ P＞0．05）。结论：氟离子导入与1．23％氟化泡沫对早期人工根面龋均有明显再矿化作用，两者再矿化效果无显著差异。
목적：체외실험비교불리자도입여불화포말대인공근면우재광화작용적차이，탐토불리자도입적작용궤제。방법：제비인공조기근면우모형35개，수궤분위5조：공백대조조、1．23％불화포말조、불리자도입조、불화납용액조급생리염수도입조。각조양본경과pH순배처리후，우소묘전경화격광공취초현미경하박섭도상，병분석결과。결과：불리자도입조급불화포말조양품표면교기여각조광활，가견명현적재광화침적물；이자탈광심도여형광면적상대우기여각조현저감소（P＜0．01），단량조간무현저차이（ P＞0．05）。결론：불리자도입여1．23％불화포말대조기인공근면우균유명현재광화작용，량자재광화효과무현저차이。
Objective:To investigate the relationship between fluoride iontophoresis and remineralization of human root caries in vitro.Methods:Thirty-five human root samples were demineralized by acid-etching, randomly divided into five groups , then pretreated with 1.23%fluoride foam, 4%NaF solution with iontophoresis , 4%NaF solution simply and physiological saline with iontophoresis re-spectively.Then the samples were remineralized by pH-cycling, and the effects of remineralization were analyzed by laser scanning confocal microscope (LSCM) while lesions were photoed by scanning electronic microscope (SEM).Results:Observed by SEM, the two groups pretreated with 1.23%fluoride foam and 4%NaF solution with iontophoresis had smoother surfaces and they had significant differences in reducing demineralized depth and area compared with other groups (P<0.01)analyzed by LSCM, but there was no sig-nificant difference between themselves (P>0.05).Conclusions:Both fluoride iontophoresis and fluoride foam can promote remineral-ization of root caries , but have no significant differences in reducing demineralized depth and area .