CAJ | 학술논문

目的：探讨无肝素化持续血液滤过在产后大出血、多脏器功能不全产妇中的应用效果。方法采用前后对照法，比较2010年采用肝素抗凝持续血液滤过治疗的产妇（对照组）与2013年采用无肝素化持续血液滤过治疗的产妇（观察组）伤口、阴道流血情况以及凝血功能检查情况。结果观察组产后大出血、多脏器功能不全产妇的伤口、阴道流血明显较对照组少，差异有显著意义（ P＜0．001）；观察组产后大出血、多脏器功能不全产妇的活化部分凝血活酶时间测定明显降低（ P＜0．001）。结论无肝素化持续血液滤过治疗能有效减少病人出血等并发症发生。
목적：탐토무간소화지속혈액려과재산후대출혈、다장기공능불전산부중적응용효과。방법채용전후대조법，비교2010년채용간소항응지속혈액려과치료적산부（대조조）여2013년채용무간소화지속혈액려과치료적산부（관찰조）상구、음도류혈정황이급응혈공능검사정황。결과관찰조산후대출혈、다장기공능불전산부적상구、음도류혈명현교대조조소，차이유현저의의（ P＜0．001）；관찰조산후대출혈、다장기공능불전산부적활화부분응혈활매시간측정명현강저（ P＜0．001）。결론무간소화지속혈액려과치료능유효감소병인출혈등병발증발생。
Objective To study the advantages of applying non-heparin continuous hemodialysis for postpartum hemorrhage and multiple organ dysfunction .Method 53 patients with severe obstetrical and gynaecological diseases in 2007 was selected compared with the similar patients in 2013 ,the heparin continuous hemofiltration for patients in 2007 ,the non-heparin continuous hemodialysis for patients in 2013 .Compare the wound ,aginal bleeding of patients and conduct coagulation tests to check their conditions .Result The two groups of patients have significantly different in wound ,aginal bleeding (P< 0 .001) .There were also significant different in coagulation tests results (P<0 .001) .Conclusion The therapy of non-heparin continuous hemodialysis can effectively lower the incidences of haem-orrhages and other complications for patients with severe obstetrical and gynaecological diseases .