中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2013年
z1期
5-7
,共3页
大肠埃希菌%药敏试验%超广谱β-内酰胺酶%耐药性
大腸埃希菌%藥敏試驗%超廣譜β-內酰胺酶%耐藥性
대장애희균%약민시험%초엄보β-내선알매%내약성
Escherichia coli%Drug sensitive test%Extended-spectrum β-lactamase%Resistance
目的 分析临床分离大肠埃希菌的分布及药敏情况.方法 采集2010年1月至2011年7月临床各科送检细菌培养标本,进行大肠埃希菌的分离、培养,采用黑马微生物分析系统对大肠埃希菌进行筛选鉴定及药敏监测.结果 从临床标本分离出的大肠埃希菌486株,其中男297例,女189例,外科分泌物标本236株(占48.56％),呼吸内科的痰165株(占33.95％),泌尿外科的尿液39株(占8.02％)、其他样本46株(占9.47％).产ESBLs大肠埃希菌198株(占40.74％)；产ESBLs大肠埃希菌株对19种抗生素的耐药性均高于大肠埃希菌株,产ESBLs大肠埃希菌对氨基糖苷类、喹诺酮类等抗菌药呈多重耐药,大肠埃希菌株均对亚胺培南敏感.结论 经手术、呼吸道、尿路产生的大肠埃希菌占有较大比重,而且耐药现象严重,根据大肠埃希菌药敏试验合理应用抗生素,尤其是产ESBLs大肠埃希菌株,要不断加强耐药性检测,为临床合理用药提供参考.
目的 分析臨床分離大腸埃希菌的分佈及藥敏情況.方法 採集2010年1月至2011年7月臨床各科送檢細菌培養標本,進行大腸埃希菌的分離、培養,採用黑馬微生物分析繫統對大腸埃希菌進行篩選鑒定及藥敏鑑測.結果 從臨床標本分離齣的大腸埃希菌486株,其中男297例,女189例,外科分泌物標本236株(佔48.56％),呼吸內科的痰165株(佔33.95％),泌尿外科的尿液39株(佔8.02％)、其他樣本46株(佔9.47％).產ESBLs大腸埃希菌198株(佔40.74％)；產ESBLs大腸埃希菌株對19種抗生素的耐藥性均高于大腸埃希菌株,產ESBLs大腸埃希菌對氨基糖苷類、喹諾酮類等抗菌藥呈多重耐藥,大腸埃希菌株均對亞胺培南敏感.結論 經手術、呼吸道、尿路產生的大腸埃希菌佔有較大比重,而且耐藥現象嚴重,根據大腸埃希菌藥敏試驗閤理應用抗生素,尤其是產ESBLs大腸埃希菌株,要不斷加彊耐藥性檢測,為臨床閤理用藥提供參攷.
목적 분석림상분리대장애희균적분포급약민정황.방법 채집2010년1월지2011년7월림상각과송검세균배양표본,진행대장애희균적분리、배양,채용흑마미생물분석계통대대장애희균진행사선감정급약민감측.결과 종림상표본분리출적대장애희균486주,기중남297례,녀189례,외과분비물표본236주(점48.56％),호흡내과적담165주(점33.95％),비뇨외과적뇨액39주(점8.02％)、기타양본46주(점9.47％).산ESBLs대장애희균198주(점40.74％)；산ESBLs대장애희균주대19충항생소적내약성균고우대장애희균주,산ESBLs대장애희균대안기당감류、규낙동류등항균약정다중내약,대장애희균주균대아알배남민감.결론 경수술、호흡도、뇨로산생적대장애희균점유교대비중,이차내약현상엄중,근거대장애희균약민시험합리응용항생소,우기시산ESBLs대장애희균주,요불단가강내약성검측,위림상합리용약제공삼고.
Objective To analyze the distribution and drug resistance of Escherichia coli which separated from clinical.Methods Collecting the bacteria specimens to separating and training Escherichia coli,and then screening and monitoring drug susceptibility by The Dark Horse Microbial Analysis System,from January 2010 to July 2011.Results The Escherichia coli 486 strains which separated from clinical,the male 297 cases,female 189 cases,secretion separation 236 strains was the highest rate (48.56％),sputum 165 strains (33.95％),urine 39 strains (8.02％),and the rest of the sample 46 strains (9.47％).ESBLs 198 strains,which resistance in 19 antibiotics were higher than Escherichia coli,and it was multiple antibiotic resistance such as Aminoglycoside,Quinolone etc; Escherichia coli strains were sensitive to imipenem.Conclusion Escherichia coli which separated in surgery,respiratory tract,and urinary had a large proportion,and Resistance of Escherichia coli was serious,we should according to the Drug sensitivity of Escherichia coli,choose reasonable application of antibiotics,especially the ESBLs strains.We should strengthen the resistance testing,to provide reference for clinical rational drug use.
