重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
5期
592-593,596
,共3页
何盛华%周锐锋%刘大凤%蔡林%王印%周晓飞%张毅%张春兰%刘晓霞%张峣
何盛華%週銳鋒%劉大鳳%蔡林%王印%週曉飛%張毅%張春蘭%劉曉霞%張峣
하성화%주예봉%류대봉%채림%왕인%주효비%장의%장춘란%류효하%장요
获得性免疫缺陷综合征%机会性感染%临床特点%预后
穫得性免疫缺陷綜閤徵%機會性感染%臨床特點%預後
획득성면역결함종합정%궤회성감염%림상특점%예후
acquired immunodeficiency syndrome%opportunistic infections%clinical characters%prognosis
目的：探讨四川地区艾滋病（A ID S ）患者合并机会性感染的临床特点及其对预后的影响。方法回顾性分析成都市传染病医院近10年1465例AIDS住院患者合并机会性感染的临床资料。结果 AIDS合并机会性感染患者住院期间总病死率15．49％，导致死亡的常见机会性感染是重症肺炎150例（74．62％）、中枢神经系统感染47例（23．86％）；常见的疾病种类是细菌性肺炎、肺孢子菌肺炎、深部真菌病、结核病；常见的感染部位是呼吸道、口咽部、中枢神经系统、消化道、皮肤。同时患两种及以上的机会性感染疾病占50．77％；感染同时累及2个部位占42．18％、3个及以上占17．20％。结论四川地区AIDS患者合并机会性感染具有自身的临床特点，多部位及多种感染同时存在、病情复杂严重，是目前A ID S患者死亡的主要原因。
目的：探討四川地區艾滋病（A ID S ）患者閤併機會性感染的臨床特點及其對預後的影響。方法迴顧性分析成都市傳染病醫院近10年1465例AIDS住院患者閤併機會性感染的臨床資料。結果 AIDS閤併機會性感染患者住院期間總病死率15．49％，導緻死亡的常見機會性感染是重癥肺炎150例（74．62％）、中樞神經繫統感染47例（23．86％）；常見的疾病種類是細菌性肺炎、肺孢子菌肺炎、深部真菌病、結覈病；常見的感染部位是呼吸道、口嚥部、中樞神經繫統、消化道、皮膚。同時患兩種及以上的機會性感染疾病佔50．77％；感染同時纍及2箇部位佔42．18％、3箇及以上佔17．20％。結論四川地區AIDS患者閤併機會性感染具有自身的臨床特點，多部位及多種感染同時存在、病情複雜嚴重，是目前A ID S患者死亡的主要原因。
목적：탐토사천지구애자병（A ID S ）환자합병궤회성감염적림상특점급기대예후적영향。방법회고성분석성도시전염병의원근10년1465례AIDS주원환자합병궤회성감염적림상자료。결과 AIDS합병궤회성감염환자주원기간총병사솔15．49％，도치사망적상견궤회성감염시중증폐염150례（74．62％）、중추신경계통감염47례（23．86％）；상견적질병충류시세균성폐염、폐포자균폐염、심부진균병、결핵병；상견적감염부위시호흡도、구인부、중추신경계통、소화도、피부。동시환량충급이상적궤회성감염질병점50．77％；감염동시루급2개부위점42．18％、3개급이상점17．20％。결론사천지구AIDS환자합병궤회성감염구유자신적림상특점，다부위급다충감염동시존재、병정복잡엄중，시목전A ID S환자사망적주요원인。
Objective To study clinical characters and prognosis of AIDS patients with opportunistic infections in Sichuan prov-ince .Methods We performed an retrospective analysis of 1 465 AIDS patients with opportunistic infections who were admitted into the transmitted disease hospital of Chengdu in recent 10 years .Results The overall mortality during hospitalization was 15 .49% . The leading cause of death was respiratory failure due to pneumonia (n=150 ,74 .62% ) or meningitis(n=47 ,23 .86% ) .Descending rank order of common opportunistic infections were respiratory tract ,the mouth swallows ,central nervous system ,gastrointestinal tract skin ,blood system .Descending rank order of common sites of infections were respiratory tract ,oropharynx ,central nervous system ,gastrointestinal tract skin ,reproductive tract .The multiple infections are common :more than 50% of patients suffering from two or more infections(50 .77% ) .Complexity of infection sites :42 .18% dual infection sites and 17 .20% three or more infec-tion sites .Conclusion The opportunistic infections disease spectrum of AIDS in Sichuan area has its own characteristics :multiple infections and multiple infections sites are both common ,death risks are high ,conditions of patients are severe generally ,and respir-atory failure is the main cause of death .
