中华临床医师杂志（电子版）
中華臨床醫師雜誌（電子版）
중화림상의사잡지（전자판）
CHINESE JOURNAL OF CLINICIANS(ELECTRONIC VERSION)
2014年
3期
502-505
,共4页
气管%灌洗%插管法,气管内%支气管镜%动物实验
氣管%灌洗%插管法,氣管內%支氣管鏡%動物實驗
기관%관세%삽관법,기관내%지기관경%동물실험
Trachea%Irrigation%Intubation,intratracheal%Bronchoscopes%Animal experimentation
目的：探讨一种简易的气管灌洗新方法的效果。方法10只健康成年比格犬随机分为两组，新方法组利用无菌胶带将一次性吸痰管固定于气管插管导管的套囊上端，吸痰管另一端连接注射器组合成简单的灌洗装置，对实验犬常规经口气管插管并对球囊充气固定，调高实验台并保持头高脚低且与水平成45°的体位，利用注射器经过吸痰管注入生理盐水至气管腔内，通过反复抽吸灌洗液或左右翻身以充分灌洗气管壁后，回抽灌洗液。对照组利用支气管镜经口进入犬气管腔内并固定，用无菌注射器经过支气管镜操作管道注入生理盐水至气管腔后，立即通过负压吸引回收灌洗液。灌洗后测量外周血氧饱和度以及进行喉部和双肺听诊，并比较两种灌洗方法的灌洗液回收率、操作时间以及术后并发症等情况。结果新方法组灌洗回收率[（91.00±0.24）%]明显高于对照组[（10.20±0.27）%]（ t=-70.69， P＜0.01）；新方法操作时间[（62.20±7.48） s/次]少于对照组[（165.46±7.83）s/次]（t=-20.68，P＜0.01）。新方法组灌洗后未出现喉部痰鸣音、双肺啰音等术后并发症，外周血氧饱和度无明显降低，灌洗前后SpO2分别为（97.52±1.33）%和（97.46±1.12）%（t=0.31，P＞0.05）；而对照组灌洗后均可闻喉部痰鸣音及双肺啰音，外周血氧饱和度降低，灌洗前后 SpO2分别为（96.67±1.63）%和（94.27±1.75）%（t=3.88，P＜0.01）。结论经气管插管行气管灌洗的方法操作简便、高效、安全可靠，可为气管疾病的诊治以及相关的实验研究提供一种气管内灌洗的新手段。
目的：探討一種簡易的氣管灌洗新方法的效果。方法10隻健康成年比格犬隨機分為兩組，新方法組利用無菌膠帶將一次性吸痰管固定于氣管插管導管的套囊上耑，吸痰管另一耑連接註射器組閤成簡單的灌洗裝置，對實驗犬常規經口氣管插管併對毬囊充氣固定，調高實驗檯併保持頭高腳低且與水平成45°的體位，利用註射器經過吸痰管註入生理鹽水至氣管腔內，通過反複抽吸灌洗液或左右翻身以充分灌洗氣管壁後，迴抽灌洗液。對照組利用支氣管鏡經口進入犬氣管腔內併固定，用無菌註射器經過支氣管鏡操作管道註入生理鹽水至氣管腔後，立即通過負壓吸引迴收灌洗液。灌洗後測量外週血氧飽和度以及進行喉部和雙肺聽診，併比較兩種灌洗方法的灌洗液迴收率、操作時間以及術後併髮癥等情況。結果新方法組灌洗迴收率[（91.00±0.24）%]明顯高于對照組[（10.20±0.27）%]（ t=-70.69， P＜0.01）；新方法操作時間[（62.20±7.48） s/次]少于對照組[（165.46±7.83）s/次]（t=-20.68，P＜0.01）。新方法組灌洗後未齣現喉部痰鳴音、雙肺啰音等術後併髮癥，外週血氧飽和度無明顯降低，灌洗前後SpO2分彆為（97.52±1.33）%和（97.46±1.12）%（t=0.31，P＞0.05）；而對照組灌洗後均可聞喉部痰鳴音及雙肺啰音，外週血氧飽和度降低，灌洗前後 SpO2分彆為（96.67±1.63）%和（94.27±1.75）%（t=3.88，P＜0.01）。結論經氣管插管行氣管灌洗的方法操作簡便、高效、安全可靠，可為氣管疾病的診治以及相關的實驗研究提供一種氣管內灌洗的新手段。
목적：탐토일충간역적기관관세신방법적효과。방법10지건강성년비격견수궤분위량조，신방법조이용무균효대장일차성흡담관고정우기관삽관도관적투낭상단，흡담관령일단련접주사기조합성간단적관세장치，대실험견상규경구기관삽관병대구낭충기고정，조고실험태병보지두고각저차여수평성45°적체위，이용주사기경과흡담관주입생리염수지기관강내，통과반복추흡관세액혹좌우번신이충분관세기관벽후，회추관세액。대조조이용지기관경경구진입견기관강내병고정，용무균주사기경과지기관경조작관도주입생리염수지기관강후，립즉통과부압흡인회수관세액。관세후측량외주혈양포화도이급진행후부화쌍폐은진，병비교량충관세방법적관세액회수솔、조작시간이급술후병발증등정황。결과신방법조관세회수솔[（91.00±0.24）%]명현고우대조조[（10.20±0.27）%]（ t=-70.69， P＜0.01）；신방법조작시간[（62.20±7.48） s/차]소우대조조[（165.46±7.83）s/차]（t=-20.68，P＜0.01）。신방법조관세후미출현후부담명음、쌍폐라음등술후병발증，외주혈양포화도무명현강저，관세전후SpO2분별위（97.52±1.33）%화（97.46±1.12）%（t=0.31，P＞0.05）；이대조조관세후균가문후부담명음급쌍폐라음，외주혈양포화도강저，관세전후 SpO2분별위（96.67±1.63）%화（94.27±1.75）%（t=3.88，P＜0.01）。결론경기관삽관행기관관세적방법조작간편、고효、안전가고，가위기관질병적진치이급상관적실험연구제공일충기관내관세적신수단。
Objective To evaluate the efficacy of a novel method of tracheal lavage. Methods 10 beagle dogs were divided into two groups, New method group: a suction catheter was adhered to the endotracheal intubation tube at the upper end of the cuff, when the cuff was full inflated with air after endotracheal intubation, sterilizing saline was injected into the tracheal lumen through the suction catheter and then recovered by syringe. Control group: sterilizing saline was injected into the tracheal lumen through the working channel of bronchoscope and then recovered by negative pressure. Oxygen saturation measurement and lung auscultation were performed after lavement, the recovery rate of tracheal lavage fluid, operating time and the postoperative complications were recorded and compared between two groups. Results The recovery rate of tracheal lavage fluid in New method group was significantly higher than that in Control group,(91.00±0.24)% and (10.20±0.27)%, respectively, t=-70.69, P<0.01. The operating time in New method group was less than that in Control group, (62.20±7.48)s/time and (165.46±7.83)s/time, respectively, t=-20.68, P<0.01. No evident showed wheezy phlegm, lung rales or reduction in oxygenation in New method group, the SpO2 before and after lavement were(97.52±1.33)%and (97.46±1.12)%, respectively, t=0.31, P>0.05. In Control group, all dogs occurred wheezy phlegm, lung rales and reduction in oxygenation, the SpO2 before and after lavement were (96.67±1.63)% and (94.27±1.75)%, respectively, t=3.88, P<0.01. Conclusion The new method of tracheal lavage by endotracheal intubation is simple, effective and reliable, it would be helpful for the further experiment research and the diagnosis and treatment of tracheal disease.
