中国医学前沿杂志（电子版）
中國醫學前沿雜誌（電子版）
중국의학전연잡지（전자판）
CHINESE JOURNAL OF THE FRONTIERS OF MEDICAL SCIENCE(ELECTRONIC VERSION)
2014年
3期
58-61
,共4页
颈动脉狭窄%支架置入术%缺血性脑血管病
頸動脈狹窄%支架置入術%缺血性腦血管病
경동맥협착%지가치입술%결혈성뇌혈관병
Carotid artery stenosis%Carotid stenting%Ischemic cerebrovascular disease
目的总结颈动脉狭窄支架成形术的经验，评价其疗效。方法根据患者临床治疗方式的不同，将本院收治的92例颈动脉狭窄患者分为两组，即支架成形术治疗组（46例），单纯药物治疗组（46例）。药物组患者行单纯药物治疗，即予以患者氯吡格雷、阿司匹林及阿托伐他汀长期维持治疗。支架成形术治疗组患者行颈动脉支架成形术（carotid artery stenting，CAS）治疗。观察支架释放成功率；治疗1个月后，分别对两组患者的颈动脉狭窄程度进行评价；同时观察并统计两组患者治疗后并发症的发生率及死亡率。另外，观察支架成形术治疗组患者支架置入后的生物相容性及不良反应发生情况。结果支架成形术治疗组支架释放成功率为100%，患者治疗后颈动脉重度狭窄的比率为2.18%，单纯药物治疗组为21.74%。两组比较，差异具有显著性（P＜0.01）。治疗后，支架成形术治疗组患者颈动脉短暂性脑缺血发作（TIA）、缺血性脑卒中、新发梗死及死亡的发生率依次为0、2.18%、2.18%、0；单纯药物治疗组依次为10.87%、6.52%、4.35%、6.52%。两组比较，差异具有显著性（P＜0.05）。支架成形术治疗组患者无特殊生物相容性反应，术后不良反应的总发生率为10.87%。结论支架成形术能有效改善患者颈动脉狭窄程度，并降低患者颈动脉TIA、缺血性脑卒中、新发梗死及死亡的发生率。
目的總結頸動脈狹窄支架成形術的經驗，評價其療效。方法根據患者臨床治療方式的不同，將本院收治的92例頸動脈狹窄患者分為兩組，即支架成形術治療組（46例），單純藥物治療組（46例）。藥物組患者行單純藥物治療，即予以患者氯吡格雷、阿司匹林及阿託伐他汀長期維持治療。支架成形術治療組患者行頸動脈支架成形術（carotid artery stenting，CAS）治療。觀察支架釋放成功率；治療1箇月後，分彆對兩組患者的頸動脈狹窄程度進行評價；同時觀察併統計兩組患者治療後併髮癥的髮生率及死亡率。另外，觀察支架成形術治療組患者支架置入後的生物相容性及不良反應髮生情況。結果支架成形術治療組支架釋放成功率為100%，患者治療後頸動脈重度狹窄的比率為2.18%，單純藥物治療組為21.74%。兩組比較，差異具有顯著性（P＜0.01）。治療後，支架成形術治療組患者頸動脈短暫性腦缺血髮作（TIA）、缺血性腦卒中、新髮梗死及死亡的髮生率依次為0、2.18%、2.18%、0；單純藥物治療組依次為10.87%、6.52%、4.35%、6.52%。兩組比較，差異具有顯著性（P＜0.05）。支架成形術治療組患者無特殊生物相容性反應，術後不良反應的總髮生率為10.87%。結論支架成形術能有效改善患者頸動脈狹窄程度，併降低患者頸動脈TIA、缺血性腦卒中、新髮梗死及死亡的髮生率。
목적총결경동맥협착지가성형술적경험，평개기료효。방법근거환자림상치료방식적불동，장본원수치적92례경동맥협착환자분위량조，즉지가성형술치료조（46례），단순약물치료조（46례）。약물조환자행단순약물치료，즉여이환자록필격뢰、아사필림급아탁벌타정장기유지치료。지가성형술치료조환자행경동맥지가성형술（carotid artery stenting，CAS）치료。관찰지가석방성공솔；치료1개월후，분별대량조환자적경동맥협착정도진행평개；동시관찰병통계량조환자치료후병발증적발생솔급사망솔。령외，관찰지가성형술치료조환자지가치입후적생물상용성급불량반응발생정황。결과지가성형술치료조지가석방성공솔위100%，환자치료후경동맥중도협착적비솔위2.18%，단순약물치료조위21.74%。량조비교，차이구유현저성（P＜0.01）。치료후，지가성형술치료조환자경동맥단잠성뇌결혈발작（TIA）、결혈성뇌졸중、신발경사급사망적발생솔의차위0、2.18%、2.18%、0；단순약물치료조의차위10.87%、6.52%、4.35%、6.52%。량조비교，차이구유현저성（P＜0.05）。지가성형술치료조환자무특수생물상용성반응，술후불량반응적총발생솔위10.87%。결론지가성형술능유효개선환자경동맥협착정도，병강저환자경동맥TIA、결혈성뇌졸중、신발경사급사망적발생솔。
Objective To summarize the experience of carotid artery stenosis stent angioplasty, and evaluate its curative effect. Methods According to the different clinical treatment, our hospital 92 cases of patients with carotid stenosis was divided into two groups, namely, stent angioplasty treatment group 46 cases, 46 cases of simple drug treatment group. Drug group of patients with simple drug treatment, shall be, thanks to aspirin and clopidogrel in patients with long-term maintenance treatment lipitor. Patients with carotid artery stent plasty group carotid stenting (carotid artery stenting, CAS) treatment. Observation stents release rate;1 month after treatment, respectively on two groups patients of carotid stenosis degree evaluation;at the same time observation and statistics of two groups after treatment in patients with the incidence of complications and mortality. In addition, observe the biocompatibility of the observation group of patients after stent implantation and adverse reactions occur. Results Stents forming group released the success rate was 100%, the ratio of carotid artery after treatment in patients with severe stenosis was 2.18%, and the drug group was 21.74%. Comparison of two groups, the difference is signiifcant (P<0.01). Group therapy, stent angioplasty in patients with carotid TIA and ischemic stroke, new hair infarction and the incidence of death in 0, 2.18%, 2.18%, 0;Drug group was 10.87%, 6.52%, 4.35%and 6.52%in turn. Comparison of two groups, the difference is statistically signiifcant (P<0.05). Stent angioplasty patients no special biocompatibility reaction, after surgery, the total incidence of adverse reactions was 10.87%. Conclusion The stent plasty can effectively improve the patient's degree of carotid stenosis, and reduce the patients with carotid TIA and ischemic stroke, new hair infarction and the incidence of death.
