CAJ | 학술논문

目的：探讨进展为帕金森病的特发性震颤的临床特点。方法回顾性分析单纯特发性震颤患者（40例）及进展为帕金森病的特发性震颤患者（16例）的临床资料，比较2组患者的发病年龄、病程、震颤类型、震颤分布范围、小脑体征、肌肉强直等，并采用日常生活能力量表（ADL ）进行生活能力评价。结果2组患者在发病年龄、性别、病程、ADL评分、小脑体征方面无显著差异。与单纯特发性震颤患者比较，进展为帕金森病的特发性震颤患者帕金森病家族史、帕金森病样症状更为常见（ P＜0.05）。2组患者震颤部位均以上肢常见，单纯特发性震颤患者较进展为帕金森病的特发性震颤患者姿势性或动作性震颤所占比例增高，震颤分布范围更加广泛，易累及头部、咽喉、下肢等多个部位（ P＜0.05）。结论进展为帕金森病的特发性震颤患者具有帕金森病样表现。
목적：탐토진전위파금삼병적특발성진전적림상특점。방법회고성분석단순특발성진전환자（40례）급진전위파금삼병적특발성진전환자（16례）적림상자료，비교2조환자적발병년령、병정、진전류형、진전분포범위、소뇌체정、기육강직등，병채용일상생활능역량표（ADL ）진행생활능력평개。결과2조환자재발병년령、성별、병정、ADL평분、소뇌체정방면무현저차이。여단순특발성진전환자비교，진전위파금삼병적특발성진전환자파금삼병가족사、파금삼병양증상경위상견（ P＜0.05）。2조환자진전부위균이상지상견，단순특발성진전환자교진전위파금삼병적특발성진전환자자세성혹동작성진전소점비례증고，진전분포범위경가엄범，역루급두부、인후、하지등다개부위（ P＜0.05）。결론진전위파금삼병적특발성진전환자구유파금삼병양표현。
Objective To explore the clinical characteristic of patients with essential tremor developing into Parkinson ’s disease (ET-PD).Methods Forty cases with ET and sixteen cases with ET-PD were retrospectively reviewed. In the two groups , features such as age at onset ,duration ,the type of tremor ,the location of tremor ,cerebellar signs ,and rigidity were compared. ADL was used to evaluate the activity of daily living.Results T he patients in the two groups had similar age ,gender ,duration ,ADL scores and cerebrella signs. Family history of PD and signs of parkinson-ism were more common in ET-PD than ET patients(P<0.05). Upper limb tremor was common in the two groups. More ET than ET-PD had widespread postural and/or action tremor. The tremor included the head ,voice ,and legs(P<0.05).Conclusion ET-PD patients may have PD features.