CAJ | 학술논문

雌激素、孕激素受体和人表皮生长因子受体2的表达水平与乳腺癌预后关系密切，是治疗乳腺癌的重要靶点。研究发现，雄激素受体（ AR）与乳腺癌的发生、发展、复发、转移及预后转归相关，可能成为影响乳腺癌预后的一个指标。目前，AR在乳腺癌领域的研究陆续展开，已成为一个新的热点。本文就AR与乳腺癌关系的研究现状作初步探讨。
자격소、잉격소수체화인표피생장인자수체2적표체수평여유선암예후관계밀절，시치료유선암적중요파점。연구발현，웅격소수체（ AR）여유선암적발생、발전、복발、전이급예후전귀상관，가능성위영향유선암예후적일개지표。목전，AR재유선암영역적연구륙속전개，이성위일개신적열점。본문취AR여유선암관계적연구현상작초보탐토。
The expressions of estrogen receptor,progesterone receptor and human epidermal growth factor receptor 2 are not only closely associated with the prognosis of breast cancer, but also can be served as targets for breast cancer therapy. Recent studies have found that androgen receptor( AR) is associated with the occurrence, development, relapse and metastasis, as well as the progno-sis and outcome in breast cancer, and may be a prognostic predictor. Currently, AR in breast cancer is becoming a hot spot. In this pa-per, we make a preliminary discussion on relationship between AR and breast cancer.