CAJ | 학술논문

随着我国经济和社会的持续较高速度发展以及人民生活水平的提高，对食品安全提出了越来越高的要求。近年来，我国出现了许多令人忧虑的食品安全问题，食品安全风险监测工作正面临着巨大的挑战。代谢组学是通过考察生物体系受刺激或扰动后，代谢产物的变化或其随时间的变化的一个新兴的重要组学技术，在药物研究、疾病诊断、植物育种、环境科学等很多领域中得以广泛应用。本文在介绍了目前我国食品安全监测中存在的问题之后，对代谢组学技术在食品安全领域中的应用研究进行了全面的综述，表明了代谢组学技术在食品中兽药残留、禁用物质、转基因食品、食品掺假和食源性疾病等检测方面有着良好的应用前景，但在实际应用中依然存在一些问题有待进一步研究，为应用代谢组学开展食品安全风险监测与评估提供一定的参考。
수착아국경제화사회적지속교고속도발전이급인민생활수평적제고，대식품안전제출료월래월고적요구。근년래，아국출현료허다령인우필적식품안전문제，식품안전풍험감측공작정면림착거대적도전。대사조학시통과고찰생물체계수자격혹우동후，대사산물적변화혹기수시간적변화적일개신흥적중요조학기술，재약물연구、질병진단、식물육충、배경과학등흔다영역중득이엄범응용。본문재개소료목전아국식품안전감측중존재적문제지후，대대사조학기술재식품안전영역중적응용연구진행료전면적종술，표명료대사조학기술재식품중수약잔류、금용물질、전기인식품、식품참가화식원성질병등검측방면유착량호적응용전경，단재실제응용중의연존재일사문제유대진일보연구，위응용대사조학개전식품안전풍험감측여평고제공일정적삼고。
The quality and safety of food is a major benchmark of the economic development and people’s living conditions of a country. In recent years, several cases of the food scandal have been disclosed on various media. Food safety risk monitoring work is facing the huge challenge. Metabonomics mainly investigates the change of endogenous metabolism of biological system that is stimulated or disturbed, and studies the meta-bolic pathways of biological system. Metabonomics is an emerged important research tool of system biology in drug discovery, disease diagnosis, plant breeding and environmental science. In this review, we gave an over-view of some food safety problems that have had a major impact on public health over the last several years in China and how metabonomics can be used to tackle the issue of food safety. The review showed that metabo-nomics had favorable the applying prospects in residues of veterinary drugs, banned substances, genetically modified food, food adulteration, foodborne illnesses. However, there were some problems in the practical ap-plication, which needed to be further in-depth study. This review may be valuable for the further study.