CAJ | 학술논문

为了探讨新型免疫增强剂——苷肽注射液对犬免疫功能的影响，以20只健康犬为研究对象，随机分为四组，每组5只，分别注射苷肽注射液、苷肽注射液和犬五联疫苗、犬五联疫苗、生理盐水，各组犬于注射后0、2、7、15、21d采血，检测不同组间的IL-2分泌情况。结果表明：苷肽注射液单独应用及其与疫苗联合应用，在注射后2d就可以显著提高IL-2水平，并且可以维持15d；注射苷肽注射液联合犬五联疫苗组和单独注射苷肽注射液组IL-2水平显著高于单独注射犬五联疫苗组（P〈0．05），说明苷肽注射液可以提高犬IL-2的水平，具有提高细胞免疫的作用。
위료탐토신형면역증강제——감태주사액대견면역공능적영향，이20지건강견위연구대상，수궤분위사조，매조5지，분별주사감태주사액、감태주사액화견오련역묘、견오련역묘、생리염수，각조견우주사후0、2、7、15、21d채혈，검측불동조간적IL-2분비정황。결과표명：감태주사액단독응용급기여역묘연합응용，재주사후2d취가이현저제고IL-2수평，병차가이유지15d；주사감태주사액연합견오련역묘조화단독주사감태주사액조IL-2수평현저고우단독주사견오련역묘조（P〈0．05），설명감태주사액가이제고견IL-2적수평，구유제고세포면역적작용。
In order to explore the influence of glucoside peptide injection-a new immune strengthening agent on immune function of canine, twenty canines were randomly divided into four groups in this experiment. There were five canines in each group. The canines in four groups were respectively injected with glucoside peptide injection, glueoside peptide injection combined with pentavalent vaccine in canine, pentavalent vaccine in canine and normal saline. In order to detect the IL -2 secretion, the blood was collected before injection and on the second day, the seventh day, the fifteen day and the twenty - one day after injection. The results showed that IL - 2 secretion level was significantly raised on the second day and maintained for 15 days, IL -2 secretion level of canines in the group of glucoside peptide injection and the group of glucoside peptide injection combined with pentavalent vaccine was higher than canines in the group of canine pentavalent vaccine （ P 〈 0.05 ）. This explained that glucoside peptide injection possessed the action of intensifying immunity. The results showed that the glucoside peptide injection can play its role of cell immunity enhancement by improving the dog＇ s level of IL -2.