CAJ | 학술논문

综述了基因工程菌Lactococcus lactis NZ9000在基因组学、安全性、功能性、疫苗载体构建、菌株改造等方面的研究进展，对NZ9000作为口服疫苗载体的表达系统进行了评述，展望了其在生物制药、疫苗开发和食品工业等领域的应用前景，并对今后研究的发展方向做了分析。
종술료기인공정균Lactococcus lactis NZ9000재기인조학、안전성、공능성、역묘재체구건、균주개조등방면적연구진전，대NZ9000작위구복역묘재체적표체계통진행료평술，전망료기재생물제약、역묘개발화식품공업등영역적응용전경，병대금후연구적발전방향주료분석。
Advances in genomics, safety, functionality, vaccine vehicle construction and strain improvement of genetically engineered bacteria lactococcus lactis NZ9000 were reviewed. The gene expression system of NZ9000 as oral vaccine delivery vehicle was discussed and its application prospects in the fields of bio -pharmaceuticals, vaccine development and food industry were proposed and its research development in the future was also briefly analyzed.