CAJ | 학술논문

　　目的：探讨前列消癥汤对激素难治性前列腺癌的治疗作用。方法：将确诊为激素难治性前列腺癌患者63例，随机分为2组，西医对照组采用单纯西医治疗，中西医治疗组在西医治疗基础上联合应用前列消癥汤治疗，治疗周期为3个月。治疗前后观察两组患者前列腺特异性抗原（PSA）水平、生活质量和疾病相关的心理焦虑状态。结果：治疗后，中西医治疗组PSA基本保持稳定，并显著低于西医对照组（P＜0.05）；各项生活质量均得到显著改善，较西医对照组为优（P＜0.05）；疾病相关焦虑状态得到明显改善，并显著低于西医对照组（P＜0.05）。结论：前列消癥汤对激素难治性前列腺癌具有一定的治疗作用，能够提高患者生活质量，减少疾病相关焦虑。
　　목적：탐토전렬소징탕대격소난치성전렬선암적치료작용。방법：장학진위격소난치성전렬선암환자63례，수궤분위2조，서의대조조채용단순서의치료，중서의치료조재서의치료기출상연합응용전렬소징탕치료，치료주기위3개월。치료전후관찰량조환자전렬선특이성항원（PSA）수평、생활질량화질병상관적심리초필상태。결과：치료후，중서의치료조PSA기본보지은정，병현저저우서의대조조（P＜0.05）；각항생활질량균득도현저개선，교서의대조조위우（P＜0.05）；질병상관초필상태득도명현개선，병현저저우서의대조조（P＜0.05）。결론：전렬소징탕대격소난치성전렬선암구유일정적치료작용，능구제고환자생활질량，감소질병상관초필。
Objective To evaluate the effect of Qianliexiaozheng (前列消癥) decoction on treating hor-mone-refractory prostate cancer. Methods Sixty three patients with hormone-refractory prostate cancer were divided into 2 groups randomly. Patients in control group were treated by western medicine while other patients in integration of Chinese and western medicine (ICW) group were treated by Qianliexiaozheng (前列消癥) de-coction in addition to western medicine for 3 months. Serum prostate specific antigen (PSA) levels, quality of life and anxiety state related to disease were assessed in each group before and after treatment. Results After 3-month treatment, the patients' PSA levels in ICW group didn't show significant changes compared with base-line and were lower than those in control group significantly (P<0.05); the quality of life and anxiety related to disease in ICW group was dramatically improved and presented superiority as compared to counterparts in con-trol group (P<0.05). Conclusion Qianliexiaozheng (前列消癥) decoction has a positive effect on treating hormone-refractory prostate cancer, improving the quality of life and relieving anxiety.