CAJ | 학술논문

目的：观察对胃癌患者实施术后化疗联合DC-CIK生物治疗的临床效果，并对比分析生物治疗的临床作用。方法：选取我院2010年1月至2013年10月收治入院的胃癌患者58例，随机分为观察组与对照组，两组患者均进行手术治疗，对照组患者术后单纯应用化疗，观察组在对照组基础上联合DC-CIK生物治疗，对比观察两组患者临床疗效。结果：观察组患者治疗后临床疗效优于对照组，但差异不具有统计学意义（ P＞0．05）；其生存质量评分明显高于对照组，不良反应少于对照组，P＜0．05，差异有统计学意义。结论：在对胃癌患者进行常规术后化疗基础上，联合应用DC-CIK生物治疗技术，虽不能明显提升临床疗效，但可以有效减少化疗不良反应，明显的改善患者的生存质量，具有理想的临床疗效。
목적：관찰대위암환자실시술후화료연합DC-CIK생물치료적림상효과，병대비분석생물치료적림상작용。방법：선취아원2010년1월지2013년10월수치입원적위암환자58례，수궤분위관찰조여대조조，량조환자균진행수술치료，대조조환자술후단순응용화료，관찰조재대조조기출상연합DC-CIK생물치료，대비관찰량조환자림상료효。결과：관찰조환자치료후림상료효우우대조조，단차이불구유통계학의의（ P＞0．05）；기생존질량평분명현고우대조조，불량반응소우대조조，P＜0．05，차이유통계학의의。결론：재대위암환자진행상규술후화료기출상，연합응용DC-CIK생물치료기술，수불능명현제승림상료효，단가이유효감소화료불량반응，명현적개선환자적생존질량，구유이상적림상료효。
Objective:To observe the clinical effect of postoperative chemotherapy combined with DC-CIK biotherapy in treating patients with stomach cancer , and make comparative analysis on clinical function of biotherapy .Method:58 cases with stomach cancer treated in our hospital from January 2010 to October 2013 were selected and divided into two groups randomly , the control group and the observation group .Two groups received operation treatment .The control group received single chemotherapy after operation , and the observation group received DC-CIK biotherapy based on the control group .The clinical efficacy of two groups was compared .Result: The clinical efficacy of the observation group was better than that of the control group, but the difference had no statistical significance (P﹥0.05).The life quality score of the observation group was evidently higher than that of the control group , and the adverse reactions were less than that of the control group, P ﹤0.05, which had statistical significance .Conclusion: Applying DC-CIK biotherapy based on conventional postoperative chemotherapy to patients with stomach cancer can ’ t evidently improve the clinical efficacy , but it can effectively reduce the adverse reactions and evidently improve the life quality of patients, which has ideal clinical efficacy .