中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
13期
1941-1942
,共2页
胃肠疾病%食物过敏%免疫球蛋白G
胃腸疾病%食物過敏%免疫毬蛋白G
위장질병%식물과민%면역구단백G
Gastrointestinal diseases%Food hypersensitivity%Immunoglobulin G
目的 探讨儿童功能性胃肠病与食物过敏的关系及近期预后.方法 选取108例功能性胃肠病患儿作为观察组,健康儿童36例为对照组.采用ELISA法对10种过敏食物进行IgG抗体浓度水平及血清总IgE水平进行检测,采用不同方法对患者进行健康饮食指导,3~6个月后比较两组的症状改善情况.结果 观察组1 ~10种不等的食物过敏原特异性IgG升高的患儿有90例,占83.3%,而对照组有9例,仅占25.0%(x2=20.87,P<0.05).观察组中敏感性最高的是牛奶、蛋清/黄,分别为84例(77.8%)和60例(55.6%).两组比较,均P<0.05.观察组与对照组血清总IgE水平比较,P>0.05.经饮食指导后17例(15.7%)在1个月内症状有所改善,13例(12.1%)在3个月内症状改善21例(19.4%)患者症状在3个月后无改善.总有效率为80.6%.结论 功能性胃肠病患儿易发生食物过敏且以多种食物过敏为主,IgG抗体水平的检测能够正确反应两者的关系,合理饮食结构可改善功能性胃肠病症状.
目的 探討兒童功能性胃腸病與食物過敏的關繫及近期預後.方法 選取108例功能性胃腸病患兒作為觀察組,健康兒童36例為對照組.採用ELISA法對10種過敏食物進行IgG抗體濃度水平及血清總IgE水平進行檢測,採用不同方法對患者進行健康飲食指導,3~6箇月後比較兩組的癥狀改善情況.結果 觀察組1 ~10種不等的食物過敏原特異性IgG升高的患兒有90例,佔83.3%,而對照組有9例,僅佔25.0%(x2=20.87,P<0.05).觀察組中敏感性最高的是牛奶、蛋清/黃,分彆為84例(77.8%)和60例(55.6%).兩組比較,均P<0.05.觀察組與對照組血清總IgE水平比較,P>0.05.經飲食指導後17例(15.7%)在1箇月內癥狀有所改善,13例(12.1%)在3箇月內癥狀改善21例(19.4%)患者癥狀在3箇月後無改善.總有效率為80.6%.結論 功能性胃腸病患兒易髮生食物過敏且以多種食物過敏為主,IgG抗體水平的檢測能夠正確反應兩者的關繫,閤理飲食結構可改善功能性胃腸病癥狀.
목적 탐토인동공능성위장병여식물과민적관계급근기예후.방법 선취108례공능성위장병환인작위관찰조,건강인동36례위대조조.채용ELISA법대10충과민식물진행IgG항체농도수평급혈청총IgE수평진행검측,채용불동방법대환자진행건강음식지도,3~6개월후비교량조적증상개선정황.결과 관찰조1 ~10충불등적식물과민원특이성IgG승고적환인유90례,점83.3%,이대조조유9례,부점25.0%(x2=20.87,P<0.05).관찰조중민감성최고적시우내、단청/황,분별위84례(77.8%)화60례(55.6%).량조비교,균P<0.05.관찰조여대조조혈청총IgE수평비교,P>0.05.경음식지도후17례(15.7%)재1개월내증상유소개선,13례(12.1%)재3개월내증상개선21례(19.4%)환자증상재3개월후무개선.총유효솔위80.6%.결론 공능성위장병환인역발생식물과민차이다충식물과민위주,IgG항체수평적검측능구정학반응량자적관계,합리음식결구가개선공능성위장병증상.
Objective To study the relationship between the functional gastrointestinal disease of children and food allergies,and recent prognosis.Methods 108 children with functional gastrointestinal disease were selected as the observation group,at the same time 36 healthy cases were selected as control group.ELISA was used to detect IgG antibody concentration and total IgE level in ten kinds of allergy food.The different methods were used to guide the patients' diet,the improved quality were oberseved in the two groups after 3 ~6 months.Results In the observation group 108 cases of children with functional gastrointestinal disease,1 ~ 10 kinds of inequality of food allergen specific IgG children have increased in 90 cases,accounting for 83.3%,whereas the control group had 9 cases,only accounting for 25.0% (x2 =20.87,P < 0.05).In the observation group,the foods with highest sensitivity were milk,egg white/yellow,respectively for 84 patients (77.8%) and 60 cases (55.6%).Serum total IgE level between the observation group and control group had no significant difference (P > 0.05).17 cases (15.7%) within one month,the symptoms were improved,13 cases (12.1%) in three months,the symptoms were improved,the symptoms of 21 cases (19.4%) were not improved after 3 months.The total effective rate was 80.6%.Conclusions Children with functional gastrointestinal decease is easily to occur allergy caused by different food,and IgG antibody level can correctly reflect the relationship between them,reasonable diet can improve the symptoms of functional gastrointestinal disease.