CAJ | 학술논문

目的：观察夏季三伏离子仪导入中药穴位敷贴防治小儿反复呼吸道感染的临床疗效。方法采用前瞻性研究、敷贴前后自身对照及重复测量法，多中心临床收集120例反复呼吸道感染患儿，借助离子导入仪，进行中药穴位敷贴，敷贴后随访1年，观察敷贴前、后呼吸道感染的疾病计分、全年发病次数、发作期平均病程、发作期给药途径、中医症状及体征，并检测患儿敷贴前后唾液sIgA。结果①该法总有效率65.3%；②与敷贴前相比，敷贴后疾病计分明显下降（P<0.01）；③敷贴后上呼吸道感染、支气管炎和肺炎的全年发病次数减少（P<0.01）；发作期平均病程明显缩短（P<0.01）；发作期给药途径由静滴向口服转变（P<0.01）；④多汗症状明显改善（P<0.01）；⑤该法对升高唾液sIgA作用维持半年左右。结论夏季三伏穴位敷贴防治小儿反复呼吸道感染是有效的临床手段，对升高唾液sIgA作用可持续半年左右。
목적：관찰하계삼복리자의도입중약혈위부첩방치소인반복호흡도감염적림상료효。방법채용전첨성연구、부첩전후자신대조급중복측량법，다중심림상수집120례반복호흡도감염환인，차조리자도입의，진행중약혈위부첩，부첩후수방1년，관찰부첩전、후호흡도감염적질병계분、전년발병차수、발작기평균병정、발작기급약도경、중의증상급체정，병검측환인부첩전후타액sIgA。결과①해법총유효솔65.3%；②여부첩전상비，부첩후질병계분명현하강（P<0.01）；③부첩후상호흡도감염、지기관염화폐염적전년발병차수감소（P<0.01）；발작기평균병정명현축단（P<0.01）；발작기급약도경유정적향구복전변（P<0.01）；④다한증상명현개선（P<0.01）；⑤해법대승고타액sIgA작용유지반년좌우。결론하계삼복혈위부첩방치소인반복호흡도감염시유효적림상수단，대승고타액sIgA작용가지속반년좌우。
Objective To observe the clinical effect of treating children’s recurrent respiratory tract infections (RRTI)by acupoint application with herbal ion penetration therapy in dog days. Methods This intervention was designed as a self control trial. It polycentricly selected 120 cases of child patients who met the inclusion criteria and treated them with the external treatment. Followed up for 1 year. Before and after the treatment,it was to observe the disease score,the frequency of respiratory tract infection,the acute course,ways of drug delivery,signs and symptoms of TCM,and to detect the salivary sIgA. Results ① The total effective rate was 65. 3%;② The disease score significantly decreased after treatment (P<0.001);③ After treatment,the disease score,the frequency,and the acute course declined(P<0.001);in the infection period,average number of days of treatment significantly reduced (P<0.001) and ways of drug delivery changed from the intravenous administration to oral medication,the difference was particularly significant(P<0.001);④Sweat symptoms improved significantly(P<0.001);⑤It can persistently rise the salivary sIgA in about half a year. Conclusion Acupoint application therapy for children’s RRTI in dog days is an effective clinical treatment in the prevention and treatment of children’s RRTI,while it can persistently rise the salivary sIgA in just about half a year.