CAJ | 학술논문

目的：观察清开灵颗粒联合利巴韦林注射液治疗普通型手足口病的疗效。方法：将2011年1月-2012年9月门诊符合手足口病普通型诊断标准的110例患儿随机分为对照组和治疗组两组，两组均给予退热、多饮水等对症、支持治疗，血象升高提示细菌感染者予以适当抗生素治疗。对照组给予利巴韦林注射液10～15mg/kg加入5%葡萄糖液静脉滴注，1次/d。治疗组在对照组基础上加用清开灵颗粒0.5～1袋/次，2～3次/d，口服。两组疗程均为1周。结果：治疗组55例，治愈41例，有效12例，无效2例，总有效率96.36%；对照组55例，治愈32例，有效15例，无效8例，总有效率85.45%。治疗组在总有效率及退热、疱疹结痂、口腔溃疡时间方面均优于对照组（P<0.05或 P<0.01）。结论：清开灵颗粒联合利巴韦林注射液治疗普通型手足口病疗效较好，值得临床应用。
목적：관찰청개령과립연합리파위림주사액치료보통형수족구병적료효。방법：장2011년1월-2012년9월문진부합수족구병보통형진단표준적110례환인수궤분위대조조화치료조량조，량조균급여퇴열、다음수등대증、지지치료，혈상승고제시세균감염자여이괄당항생소치료。대조조급여리파위림주사액10～15mg/kg가입5%포도당액정맥적주，1차/d。치료조재대조조기출상가용청개령과립0.5～1대/차，2～3차/d，구복。량조료정균위1주。결과：치료조55례，치유41례，유효12례，무효2례，총유효솔96.36%；대조조55례，치유32례，유효15례，무효8례，총유효솔85.45%。치료조재총유효솔급퇴열、포진결가、구강궤양시간방면균우우대조조（P<0.05혹 P<0.01）。결론：청개령과립연합리파위림주사액치료보통형수족구병료효교호，치득림상응용。
Objective:To observe Qingkailing particle and ribavirin injection HFMD. Methods:110 patients were randomly divided into two treatment groups and the control group, two groups were given drinking water and other symptomatic and supportive treatment, elevated blood bacterial infection for appropriate antibiotic. The control group received Ribavirin Injection 10~15mg/kg 5% glucose solution intravenously, 1 times/d. Treatment group took Qingkailing particles 0.5~1 bags/time, 2~3 times/d, orally. Results:55 patients, 41 cases were cured, effective in 12 cases, null in 2 cases , the total efficiency of 96.36%;the control group , in 55 cases, 32 cases were cured, effective in 15 cases, 8 cases for null, the total efficiency of 85.45%. The treatment group in the total efficiency and fever, herpes scab, mouth ulcers times were better than the control group (P<0.05 or P<0.01). Conclusion:Qingkailing particle and ribavirin injection have better efficacy in treating HFMD, worthy of clinical application .