CAJ | 학술논문

　　目的：探讨稳心颗粒联合胺碘酮治疗冠心病（CAD）心律失常的疗效和用药安全性。方法：将90例冠心病心律失常患者随机分为两组：观察组47例采用稳心颗粒合并胺碘酮治疗，对照组43例仅给予胺碘酮治疗。1个月为1个疗程，1个疗程后判定疗效，所有患者治疗前后均行心电图及24h动态心电图检查，观察治疗效果和主要不良反应。结果：治疗1个月后，观察组显效32例，有效12例，无效3例，总有效率为93.6%，对照组显效23例，有效13，无效7例，总有效率为83.7%，数据间差异具有统计学意义（P<0.05）。两组患者治疗期间未见明显不良反应。结论：稳心颗粒联合胺碘酮治疗冠心病心律失常疗效优于单用胺碘酮，其疗效满意，不良反应少，优于临床推广。
　　목적：탐토은심과립연합알전동치료관심병（CAD）심률실상적료효화용약안전성。방법：장90례관심병심률실상환자수궤분위량조：관찰조47례채용은심과립합병알전동치료，대조조43례부급여알전동치료。1개월위1개료정，1개료정후판정료효，소유환자치료전후균행심전도급24h동태심전도검사，관찰치료효과화주요불량반응。결과：치료1개월후，관찰조현효32례，유효12례，무효3례，총유효솔위93.6%，대조조현효23례，유효13，무효7례，총유효솔위83.7%，수거간차이구유통계학의의（P<0.05）。량조환자치료기간미견명현불량반응。결론：은심과립연합알전동치료관심병심률실상료효우우단용알전동，기료효만의，불량반응소，우우림상추엄。
Objective:To investigate the medicine efficacy and safety of the Wenxin granule and amiodarone. Methods:90 patients were randomly divided into two groups. The observation group (47 cases) was treated with Wenxin granule and amiodarone, the control group of 43 patients only received amiodarone treatment. 1 month for 1 course of treatment, a course of treatment to determine efficacy, before and after treatment, all patients underwent Holter ECG and 24h, observed treatment effects and major adverse reactions. Results:After 1 month of treatment, the observation group 32 cases markedly effective, effective in 12 cases, 3 cases were ineffective, the total efficiency was 93.6%, in the control group, markedly effective in 23 cases, effective in 13 cases, 7 cases were ineffective, the total efficiency was 83.7%, a statistically significant difference between the data (P<0.05). During the two groups of patients showed no adverse reactions. Conclusion: The efficacy of Wenxin granule and amiodarone was superior to amiodarone alone, its results were satisfactory, fewer adverse reactions, worthy of clinical practice.