CAJ | 학술논문

　　目的观察托烷司琼复合氟哌利多、地塞米松对全身麻醉子宫切除术患者术后恶心呕吐（PONV）的预防作用。方法择期全身麻醉子宫切除术60例，随机双盲分成A、B两组，每组30例，A组术前给与托烷司琼5mg，B组术前给予托烷司琼2mg、氟哌利多1.25mg、地塞米松10mg。术后随访24h，记录患者术后的PONV的发生率和情况。结果与A组相比，B组术后6h内及6~24h的PONV发生率和程度降低（P＜0.05）。结论托烷司琼复合氟哌利多、地塞米松对减少PONV的发生比单独应用托烷司琼效果更好。
　　목적관찰탁완사경복합불고리다、지새미송대전신마취자궁절제술환자술후악심구토（PONV）적예방작용。방법택기전신마취자궁절제술60례，수궤쌍맹분성A、B량조，매조30례，A조술전급여탁완사경5mg，B조술전급여탁완사경2mg、불고리다1.25mg、지새미송10mg。술후수방24h，기록환자술후적PONV적발생솔화정황。결과여A조상비，B조술후6h내급6~24h적PONV발생솔화정도강저（P＜0.05）。결론탁완사경복합불고리다、지새미송대감소PONV적발생비단독응용탁완사경효과경호。
Objective To study the effects of tropisetron combined with droperidol and dexamethasone on postoperative nausea and vomiting(PONV) after hysterectomy under general anesthesia . Methods 60 hysterectomy patients under general anesthesia were randomly divided into two groups , each group have 30 cases.The patients in group A were given tropisetron 5 mg,those in group B tropisetron 2 mg, droperidol 1.25mg and dexamethasone 10 mg, as the controls at 10 minutes before induction of general anesthesia.PONV within 24 hours was recorded .Results Compared with group A, the incidence and intensity of postoperative in 6h,6~24h PONV were significantly lower in groups of B(P<0.05). Conclusion Tropisetron combined with dexamethasone and Droperidol is better than tropisetron alone in reducing PONV after hysterectomy under general anesthesia .