中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
20期
40-40,42
,共2页
桥本甲状腺炎(HT)%甲状腺自身抗体%TPOAb%TGAb
橋本甲狀腺炎(HT)%甲狀腺自身抗體%TPOAb%TGAb
교본갑상선염(HT)%갑상선자신항체%TPOAb%TGAb
Hashimoto's thyroiditis (HT)%Thyroid autoantibodies%TPOAb%TGAb
目的?通过对桥本甲状腺炎(HT)患者血清TPOAb、TGAb的检测探讨其临床意义。方法?选取HT患者(Ⅰ组)162例,分为甲功低下组(Ⅰa组)87例和甲功正常组(Ⅰb组)75例,Ⅰa组均给予优甲乐治疗;对照组分为单纯性结节性甲状腺肿组(Ⅱ组)160例和正常体检健康人组(Ⅲ组)162例,所有的研究对象及Ⅰa组治疗6个月后均进行TPOAb、TGAb检测,并对不同组中的两种抗体情况进行观察比较。结果?Ⅰ组(Ⅰa、Ⅰb组)与Ⅱ组、Ⅲ组对比,TPOAb、TGAb的阳性率和滴度水平均有显著性差异(P<0.01);Ⅰa组中,治疗前与治疗后比较TPOAb、TGAb有显著性差异(P<0.01)。结论?TGAb和TPOAb的检测为桥本甲状腺炎的诊断及病情评价提供了重要依据。
目的?通過對橋本甲狀腺炎(HT)患者血清TPOAb、TGAb的檢測探討其臨床意義。方法?選取HT患者(Ⅰ組)162例,分為甲功低下組(Ⅰa組)87例和甲功正常組(Ⅰb組)75例,Ⅰa組均給予優甲樂治療;對照組分為單純性結節性甲狀腺腫組(Ⅱ組)160例和正常體檢健康人組(Ⅲ組)162例,所有的研究對象及Ⅰa組治療6箇月後均進行TPOAb、TGAb檢測,併對不同組中的兩種抗體情況進行觀察比較。結果?Ⅰ組(Ⅰa、Ⅰb組)與Ⅱ組、Ⅲ組對比,TPOAb、TGAb的暘性率和滴度水平均有顯著性差異(P<0.01);Ⅰa組中,治療前與治療後比較TPOAb、TGAb有顯著性差異(P<0.01)。結論?TGAb和TPOAb的檢測為橋本甲狀腺炎的診斷及病情評價提供瞭重要依據。
목적?통과대교본갑상선염(HT)환자혈청TPOAb、TGAb적검측탐토기림상의의。방법?선취HT환자(Ⅰ조)162례,분위갑공저하조(Ⅰa조)87례화갑공정상조(Ⅰb조)75례,Ⅰa조균급여우갑악치료;대조조분위단순성결절성갑상선종조(Ⅱ조)160례화정상체검건강인조(Ⅲ조)162례,소유적연구대상급Ⅰa조치료6개월후균진행TPOAb、TGAb검측,병대불동조중적량충항체정황진행관찰비교。결과?Ⅰ조(Ⅰa、Ⅰb조)여Ⅱ조、Ⅲ조대비,TPOAb、TGAb적양성솔화적도수평균유현저성차이(P<0.01);Ⅰa조중,치료전여치료후비교TPOAb、TGAb유현저성차이(P<0.01)。결론?TGAb화TPOAb적검측위교본갑상선염적진단급병정평개제공료중요의거。
Detection?the?serum?of?patients?with?Hashimoto's?thyroiditis?(HT)?of?TPOAb,?TGAb?investigate?the?clinical?signiifcance.?Methods?HT?patients?(Ⅰ?group)?162?cases,?divided?into?low?thyroid?function?group?(A)?87?cases?of?normal?thyroid?function?the?(Ⅰb?group)?75?cases,?Ⅰa?group?were?given?euthyrox?therapy;?the?control?group?divided?into?simple?nodular?goiter?group?(Ⅱ?group),?162?cases?of?the?160?cases?and?the?healthy?control?group?of?healthy?controls?(Ⅲ?group),?all?subjects?and?Ⅰa?group?after?6?months?of?treatment?were?TPOAb,?TGAb?detectionand?the?case?of?the?two?antibodies?in?different?groups?were?observed?and?compared.?Results?Ⅰ?group?(Ⅰa,?Ⅰb?group),?group?Ⅱ,?group?Ⅲ?contrast,?TPOAb,?of?TGAb?positive?rate?and?titers?were?signiifcant?differences?(P<0.01);?Ⅰa?group?before?treatment?and?after?treatment?TPOAb,?TGAb?signiifcant?difference?(P<0.01).?Conclusion?The?TGAb?and?TPOAb?detection?provides?an?important?basis?for?the?diagnosis?of?Hashimoto's?thyroiditis?and?condition?evaluation.