CAJ | 학술논문

　　目的探讨缺铁性贫血(IDA)患者巨核细胞、血小板变化状况。方法将107例IDA患者与其他贫血组、正常对照组进行血小板、巨核细胞数及巨核细胞分类结果进行比较。结果 IDA患者血小板数与另两组相比较差异均有统计学意义，巨核细胞数与其它贫血组比较差异有统计学意义，产血小板巨核细胞与其它贫血组及正常对照组比较差异有统计学意义，颗粒巨核细胞百分比与正常对照组比较差异有统计学意义，裸核巨核细胞百分比与其它贫血组相比较差异有统计学意义(P<0.05)。结论 IDA患者血小板数、产血小板巨核细胞百分率高于正常对照及其它贫血组；骨髓巨核细胞数高于其它贫血组；颗粒巨核细胞低于正常对照组；裸核巨细胞低于其它贫血组。血小板、巨核细胞增多尤是产血小板巨核细胞数增多可作为诊断IDA的参考条件。
　　목적탐토결철성빈혈(IDA)환자거핵세포、혈소판변화상황。방법장107례IDA환자여기타빈혈조、정상대조조진행혈소판、거핵세포수급거핵세포분류결과진행비교。결과 IDA환자혈소판수여령량조상비교차이균유통계학의의，거핵세포수여기타빈혈조비교차이유통계학의의，산혈소판거핵세포여기타빈혈조급정상대조조비교차이유통계학의의，과립거핵세포백분비여정상대조조비교차이유통계학의의，라핵거핵세포백분비여기타빈혈조상비교차이유통계학의의(P<0.05)。결론 IDA환자혈소판수、산혈소판거핵세포백분솔고우정상대조급기타빈혈조；골수거핵세포수고우기타빈혈조；과립거핵세포저우정상대조조；라핵거세포저우기타빈혈조。혈소판、거핵세포증다우시산혈소판거핵세포수증다가작위진단IDA적삼고조건。
Objective To investigate the changes of megacaryocyte and platelet in patients with iron deficiency anemia(IDA). Method The platelet, numbers of megacaryocyte and megakaryocytic classification in 107 cases of IDA patients were compared with other anemia patients and healthy controls. Result The number of platelets in patients with IDA compared with the other two groups were significant differences, the numbers of megacaryocyte compared with other anemia patients were significant differences, platelet-forming megakaryocyte compared with the other two groups showed significant differences, granular megakaryocyte compared with healthy controls were significant differences and the percentage of naked nucleus megakaryocyte compared with other anemia patients showed significant differences. Conclusion The numbers of platelet and the percentage of megacaryocyte in IDA patients were higher than the other two groups, megakaryocyte were higher than other anemia patients, granular megakaryocyte were lower than healthy controls and naked nucleus megakaryocyte were lower than other anemia patients. More platelet and megakaryocyte, in especial the increased platelet-forming megakaryocyte can be used as IDA diagnostic reference condition.