CAJ | 학술논문

　　目的了解不同孕期妇女血清β-hCG水平的变化与甲状腺激素水平变化之间的关系。方法随机抽取孕早期、孕中期和孕晚期妇女各50例。按不同孕期分为3组，用化学发光法分别检测其血清β-hCG水平及总T3、总T4、FT3、FT4和TSH水平，比较各组间β-hCG水平及甲状腺激素水平的变化特点。结果(1)孕早期的FT3、FT4和TSH水平与孕中期相近。(2)孕早、中期的FT3、FT4高于孕晚期，而TSH低于孕晚期。结论妊娠期母体免疫状态的改变可能才是主要因素，孕妇甲状腺功能紊乱主要由自身免疫性因素所致。
　　목적료해불동잉기부녀혈청β-hCG수평적변화여갑상선격소수평변화지간적관계。방법수궤추취잉조기、잉중기화잉만기부녀각50례。안불동잉기분위3조，용화학발광법분별검측기혈청β-hCG수평급총T3、총T4、FT3、FT4화TSH수평，비교각조간β-hCG수평급갑상선격소수평적변화특점。결과(1)잉조기적FT3、FT4화TSH수평여잉중기상근。(2)잉조、중기적FT3、FT4고우잉만기，이TSH저우잉만기。결론임신기모체면역상태적개변가능재시주요인소，잉부갑상선공능문란주요유자신면역성인소소치。
Objective Understanding pregnant women,s serum β-HCG levels in between changes in thyroid hormone levels.Methods Random pregnant early, pregnant middle and late pregnancy women in 50 cases. Different pregnancy is divided into 3 groups, respectively by using chemiluminescence detection of its serum β-HCG level and total T3and total T4, andFT3, andFT4 , TSH levels, comparisons between the groups β-HCG levels and thyroid hormone level changes. Results (1) first trimester of FT3and theFT4 , TSH levels close to the second trimester. (2) early and mid gestation FT3and theFT4 is higher than in late pregnancy, and TSH is lower than in late pregnancy . Conclusion Change of maternal immunity during pregnancy may be the main factor, women mainly caused by autoimmune factors of thyroid dysfunction.