CAJ | 학술논문

　　目的：探讨对于小儿哮喘急性发作采用高低剂量布地奈德混悬液雾化吸入进行治疗的临床效果。方法：将本院近期收治的75例小儿哮喘急性发作期患儿根据入院先后分为高剂量组（39例）与低剂量组（36例），两组患儿均在常规综合治疗基础之上进行，低剂量组给予布地奈德混悬液0.5 mg/次雾化吸入，高剂量组给予布地奈德混悬液1.0 mg/次，比较两组患儿的临床疗效。结果：两组治疗后24 h、72 h组间比较及各组前后临床表现评分比较差异具有统计学意义（P<0.05），治疗72 h两组PEF、FEV1治疗前后及治疗后组间比较差异具有统计学意义（P<0.05）。结论：对于小儿哮喘急性发作期采用高剂量布地奈德混悬液雾化吸入起效迅速，同时有着较高的安全性，值得在临床上推广使用。
　　목적：탐토대우소인효천급성발작채용고저제량포지내덕혼현액무화흡입진행치료적림상효과。방법：장본원근기수치적75례소인효천급성발작기환인근거입원선후분위고제량조（39례）여저제량조（36례），량조환인균재상규종합치료기출지상진행，저제량조급여포지내덕혼현액0.5 mg/차무화흡입，고제량조급여포지내덕혼현액1.0 mg/차，비교량조환인적림상료효。결과：량조치료후24 h、72 h조간비교급각조전후림상표현평분비교차이구유통계학의의（P<0.05），치료72 h량조PEF、FEV1치료전후급치료후조간비교차이구유통계학의의（P<0.05）。결론：대우소인효천급성발작기채용고제량포지내덕혼현액무화흡입기효신속，동시유착교고적안전성，치득재림상상추엄사용。
Objective:To explore for children with asthma acute attack with high and low dose of budesonide suspension liquid atomization inhalation treatment the clinical effect.Method:Our hospital recent treated 75 cases of pediatric asthma children with acute phase according to the hospital,who were divided into the high dose group(39 cases)and low dose group(36 cases),two groups of children were conducted on the basis of routine comprehensive treatment and low dose groups given budesonide suspension liquid atomization inhalation of 0.5 mg/time,high dose group of budesonide suspension liquid for a 1.0 mg/time,compared the clinical curative effect of two groups of children.Result:Two groups of 24 h,72 h after treatment group before and after the rush compared between each group was statistically significant(P<0.05),treatment for 72 h two groups of PEF,FEV1 and components before and after each comparison with statistical difference(P<0.05). Conclusion:For pediatric asthma acute phase using high dose of budesonide suspension liquid atomization inhalation effect quickly,at the same time have higher security,is worth popularizing in clinical use.