中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
10期
55-57
,共3页
心脏搭桥术%氟比洛芬酯%地佐辛%芬太尼%镇痛
心髒搭橋術%氟比洛芬酯%地佐辛%芬太尼%鎮痛
심장탑교술%불비락분지%지좌신%분태니%진통
Heart bypass surgery%Flurbiprofen%Dezocine%Fentanyl%Analgesic
目的：评价氟比洛芬酯联合地佐辛用于心脏搭桥术后的镇痛效果。方法：选取2011年5月-2013年6月在本院心外科择期行心脏搭桥术的患者86例，按随机数字法分为联合用药组和单一用药组，两组患者麻醉诱导和麻醉维持方法相同。联合用药组：氟比洛芬酯+地佐辛术后自控静脉镇痛；单一用药组：芬太尼术后自控静脉镇痛。术后评价两组患者镇痛效果和镇静效果，并记录不良反应情况。结果：联合用药组不同时点的疼痛评分均低于单一用药组，差异均有统计学意义（P<0.05）；联合用药组不同时点镇静评级与单一用药组比较，差异均无统计学意义（P>0.05）；联合用药组总不良反应率为11.6%，显著低于单一用药组的48.8%，差异有统计学意义（P<0.05）。结论：氟比洛芬酯联合地佐辛用于心脏搭桥术后自控静脉镇痛，具有较好的镇痛和镇静效果，能够显著降低不良反应发生率，值得临床推广。
目的：評價氟比洛芬酯聯閤地佐辛用于心髒搭橋術後的鎮痛效果。方法：選取2011年5月-2013年6月在本院心外科擇期行心髒搭橋術的患者86例，按隨機數字法分為聯閤用藥組和單一用藥組，兩組患者痳醉誘導和痳醉維持方法相同。聯閤用藥組：氟比洛芬酯+地佐辛術後自控靜脈鎮痛；單一用藥組：芬太尼術後自控靜脈鎮痛。術後評價兩組患者鎮痛效果和鎮靜效果，併記錄不良反應情況。結果：聯閤用藥組不同時點的疼痛評分均低于單一用藥組，差異均有統計學意義（P<0.05）；聯閤用藥組不同時點鎮靜評級與單一用藥組比較，差異均無統計學意義（P>0.05）；聯閤用藥組總不良反應率為11.6%，顯著低于單一用藥組的48.8%，差異有統計學意義（P<0.05）。結論：氟比洛芬酯聯閤地佐辛用于心髒搭橋術後自控靜脈鎮痛，具有較好的鎮痛和鎮靜效果，能夠顯著降低不良反應髮生率，值得臨床推廣。
목적：평개불비락분지연합지좌신용우심장탑교술후적진통효과。방법：선취2011년5월-2013년6월재본원심외과택기행심장탑교술적환자86례，안수궤수자법분위연합용약조화단일용약조，량조환자마취유도화마취유지방법상동。연합용약조：불비락분지+지좌신술후자공정맥진통；단일용약조：분태니술후자공정맥진통。술후평개량조환자진통효과화진정효과，병기록불량반응정황。결과：연합용약조불동시점적동통평분균저우단일용약조，차이균유통계학의의（P<0.05）；연합용약조불동시점진정평급여단일용약조비교，차이균무통계학의의（P>0.05）；연합용약조총불량반응솔위11.6%，현저저우단일용약조적48.8%，차이유통계학의의（P<0.05）。결론：불비락분지연합지좌신용우심장탑교술후자공정맥진통，구유교호적진통화진정효과，능구현저강저불량반응발생솔，치득림상추엄。
Objective:To investigate the analgesic effect of flurbiprofen joint dezocine in cardiac bypass surgery. Method:86 patients in cardiac surgery elective for heart bypass surgery were selected from May 2011 to June 2013 in our hospital. They were randomly divided into combination therapy group and monotherapy group according to the admission number parity. Anesthesia induction and maintenance of anesthesia on patients of two groups were in the same way. In the combination therapy group,flurbiprofen + dezocine were used in controlled intravenous analgesia after surgery. In the monotherapy group,fentanyl was used in controlled intravenous analgesia. The effects of analgesia and sedation postoperative were evaluated in the two groups. And the adverse reactions were recorded. Result:The pain scores at different time points of the combination therapy group were lower than the monotherapy group,the differences were statistically significant(P<0.05). The differences of sedation ratings at different time points between the combination therapy group and monotherapy group were not statistically significant(P>0.05). The total adverse reaction rate of the combination therapy group was 11.6%,which was significantly lower than 48.8%of the monotherapy group,the difference was statistically significant(P<0.05). Conclusion:In cardiac bypass surgery,flurbiprofen joint dezocine in controlled analgesia has better effects of analgesic and sedative. It can significantly reduce the incidence rate of adverse reactions. It is worthy of clinical use.
