CAJ | 학술논문

　　目的：探讨射频消融术联合化疗在声门型喉癌治疗中的临床价值。方法：将本院收治的73例声门型喉癌随机分为观察组和对照组，对照组给予单纯的化疗，观察组在此基础上加用射频消融术，观察两组临床疗效、预后及不良反应发生率。结果：观察组癌细胞凋亡率为（27.28±2.12）%，临床有效率为73.6%（28/38），≥Ⅲ级不良反应发生率为28.9%（11/38），对照组癌细胞凋亡率为（21.42±1.87）%，临床有效率为45.7%（16/35），≥Ⅲ级不良反应发生率为60.0%（21/35），两组比较差异有统计学意义（P<0.05）。结论：射频消融术联合化疗能显著提高声门型喉癌的临床疗效，改善患者预后，在临床中具有重要应用价值。
　　목적：탐토사빈소융술연합화료재성문형후암치료중적림상개치。방법：장본원수치적73례성문형후암수궤분위관찰조화대조조，대조조급여단순적화료，관찰조재차기출상가용사빈소융술，관찰량조림상료효、예후급불량반응발생솔。결과：관찰조암세포조망솔위（27.28±2.12）%，림상유효솔위73.6%（28/38），≥Ⅲ급불량반응발생솔위28.9%（11/38），대조조암세포조망솔위（21.42±1.87）%，림상유효솔위45.7%（16/35），≥Ⅲ급불량반응발생솔위60.0%（21/35），량조비교차이유통계학의의（P<0.05）。결론：사빈소융술연합화료능현저제고성문형후암적림상료효，개선환자예후，재림상중구유중요응용개치。
Objective:To explore the clinical value of radiofrequency ablation combined with chemotherapy in the treatment of glottic carcinoma. Method:73 cases of patients with glottic carcinoma were randomly divided into the observation group and the control group in our hospital,the control group were treated with chemotherapy,the observation group were treated with radiofrequency ablation,observed the clinical efficacy,prognosis and the incidence of adverse reactions.Result:The apoptosis rate of the observation group was(27.28±2.12)%,the clinical effective rate was 73.6%(28/38),≥Ⅲadverse reactions occur was 28.9%(11/38),the apoptosis rate of the control group was(21.42±1.87)%,the clinical effective rate was 45.7%(16/35),≥Ⅲadverse reactions occur was 60.0%(21/35),the difference between the two groups was significant(P<0.05).Conclusion:Radiofrequency ablation combined with chemotherapy can significantly improve the clinical efficacy and prognosis,it has important clinical value.