CAJ | 학술논문

　　[目的]研究黄秋葵多糖抗小鼠运动性疲劳的作用及其机理。[方法]清洁级ICR小鼠随机分为四组：黄秋葵多糖低、高剂量组（分别用黄秋葵多糖150、300mg/（kg·d））、阳性对照组（生晒参水提物200mg/（kg·d））和空白对照组（等量蒸馏水），连续灌胃21d后，测定小鼠的游泳时间、体重变化、血乳酸、血尿素氮、肝糖元指标。[结果]低、高2个剂量黄秋葵多糖均可显著延长小鼠的游泳时间（P＜0.05），降低小鼠血乳酸、血尿素氮水平（P＜0.05），并增加肝糖原含量（P＜0.05）；其作用均与阳性对照生晒参水提物相当（P＞0.05）。[结论]黄秋葵多糖具有明显的抗小鼠运动性疲劳作用，其作用机理可能通过提高肝糖原含量增加能源物质储备、增加葡萄糖的有氧分解、减少葡萄糖的无氧酵解、减少蛋白质的分解、提高产能效率而发挥作用。
　　[목적]연구황추규다당항소서운동성피로적작용급기궤리。[방법]청길급ICR소서수궤분위사조：황추규다당저、고제량조（분별용황추규다당150、300mg/（kg·d））、양성대조조（생쇄삼수제물200mg/（kg·d））화공백대조조（등량증류수），련속관위21d후，측정소서적유영시간、체중변화、혈유산、혈뇨소담、간당원지표。[결과]저、고2개제량황추규다당균가현저연장소서적유영시간（P＜0.05），강저소서혈유산、혈뇨소담수평（P＜0.05），병증가간당원함량（P＜0.05）；기작용균여양성대조생쇄삼수제물상당（P＞0.05）。[결론]황추규다당구유명현적항소서운동성피노작용，기작용궤리가능통과제고간당원함량증가능원물질저비、증가포도당적유양분해、감소포도당적무양효해、감소단백질적분해、제고산능효솔이발휘작용。
[Objective]To investigate the anti-fatigue effect of the polysaccharide from Okra in mice. [Methods] 40 male mice were randomly divided into 4 groups including low-, high-dose groups (treated with the polysaccharide from Okra at dose of 150, 300 mg/kg·d), positive control group(treated with water extract of Dried Fresh Ginseng, at dose of 200 mg/kg·d ) and control group(treated with distil ed water). Al the 4 groups were treated by gavage for continuous 21 days and tested for their weight-loaded swimming times as wel as blood urea nitrogen, blood lactic acid and hepatic glycogen levels. [Results]The groups treated with the polysaccharide from Okra significantly prolonged the exhaustive swimming time of mice, decreased the contents of both blood urea nitrogen and blood lactic acid and increased the content of hepatic glycogen, and their effects were as effective as Dried Fresh Ginseng. [Conclusion]The polysaccharide from Okra could resist fatigue in mice in a dose-dependent manner.