中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2013年
13期
1951-1953
,共3页
糖尿病%肺炎%氨溴索%头孢哌酮%舒巴坦%老年人
糖尿病%肺炎%氨溴索%頭孢哌酮%舒巴坦%老年人
당뇨병%폐염%안추색%두포고동%서파탄%노년인
Diabetes mellitus%Pneumonia%Ambroxol%Cefoperazone%Sulbactam%Aged
目的 观察盐酸氨溴索联合抗生素治疗老年糖尿病合并肺炎患者的临床效果及安全性.方法 选择老年糖尿病合并肺炎患者86例,根据治疗方案不同分为观察组和对照组.所有患者接受吸氧、吸痰、营养支持治疗以及体位引流等治疗以及针对糖尿病的基础治疗,对照组患者在此基础上采用头孢哌酮舒巴坦5.0g溶于0.9％氯化钠注射液150 ml中静脉滴注,1次/d.观察组在对照组基础上加用氨溴索注射液,40 mg/kg体质量,溶于0.9％氯化钠注射液150 ml中静脉滴注.观察治疗期间患者体温、痰、外周血中白细胞以及X线胸片的变化并记录恢复至正常水平的时间.结果 观察组中治愈37例,好转6例,有效率为100.00％；对照组中治愈28例,好转12例,治疗有效率为93.02％.观察组的治疗有效率明显高于对照组(P＜0.05).治疗期间观察组患者不良反应发生率为6.98％；对照组不良反应发生率为4.65％.两组不良反应的发生率差异无统计学意义(P＞0.05).结论 在常规应用抗生素的基础上加用盐酸氨溴索可显著提高老年糖尿病合并肺炎患者治愈率,缩短治愈时间.
目的 觀察鹽痠氨溴索聯閤抗生素治療老年糖尿病閤併肺炎患者的臨床效果及安全性.方法 選擇老年糖尿病閤併肺炎患者86例,根據治療方案不同分為觀察組和對照組.所有患者接受吸氧、吸痰、營養支持治療以及體位引流等治療以及針對糖尿病的基礎治療,對照組患者在此基礎上採用頭孢哌酮舒巴坦5.0g溶于0.9％氯化鈉註射液150 ml中靜脈滴註,1次/d.觀察組在對照組基礎上加用氨溴索註射液,40 mg/kg體質量,溶于0.9％氯化鈉註射液150 ml中靜脈滴註.觀察治療期間患者體溫、痰、外週血中白細胞以及X線胸片的變化併記錄恢複至正常水平的時間.結果 觀察組中治愈37例,好轉6例,有效率為100.00％；對照組中治愈28例,好轉12例,治療有效率為93.02％.觀察組的治療有效率明顯高于對照組(P＜0.05).治療期間觀察組患者不良反應髮生率為6.98％；對照組不良反應髮生率為4.65％.兩組不良反應的髮生率差異無統計學意義(P＞0.05).結論 在常規應用抗生素的基礎上加用鹽痠氨溴索可顯著提高老年糖尿病閤併肺炎患者治愈率,縮短治愈時間.
목적 관찰염산안추색연합항생소치료노년당뇨병합병폐염환자적림상효과급안전성.방법 선택노년당뇨병합병폐염환자86례,근거치료방안불동분위관찰조화대조조.소유환자접수흡양、흡담、영양지지치료이급체위인류등치료이급침대당뇨병적기출치료,대조조환자재차기출상채용두포고동서파탄5.0g용우0.9％록화납주사액150 ml중정맥적주,1차/d.관찰조재대조조기출상가용안추색주사액,40 mg/kg체질량,용우0.9％록화납주사액150 ml중정맥적주.관찰치료기간환자체온、담、외주혈중백세포이급X선흉편적변화병기록회복지정상수평적시간.결과 관찰조중치유37례,호전6례,유효솔위100.00％；대조조중치유28례,호전12례,치료유효솔위93.02％.관찰조적치료유효솔명현고우대조조(P＜0.05).치료기간관찰조환자불량반응발생솔위6.98％；대조조불량반응발생솔위4.65％.량조불량반응적발생솔차이무통계학의의(P＞0.05).결론 재상규응용항생소적기출상가용염산안추색가현저제고노년당뇨병합병폐염환자치유솔,축단치유시간.
Objective To observe the effect and safety of ambroxol combined with antibiotic in treatment the elderly diabetic patients complicated with pneumonia.Methods 86 elderly diabetic patients with pneumonia were selected and divided into observation group and control group according to different treatment options.All the patients were given oxygen,suction,nutrition therapy,postural drainage and basic treatment for diabetes.Cefoperazone sulbactam was given in control group,5.0g dissolved in 150 ml saline,1 time/d.Ambroxol hydrochloride injection was added in observation group,40mg/kg dissolved in 150 ml saline,1 time/d.Body temperature,sputum,leukocyte and chest X-ray were observed and recorded,and the recovery time was recorded.Results 37 cases were cured,6 cases improved in observation group,and the total effective rate was 100.00％.28 cases were cured,12 cases improved in control group,and the total effective rate was 93.02％.The effective rate of the observation group was higher than the control group(P ＜0.05).The incidence rate of adverse reactions in observation group was 6.98％,while 4.65％ in control group,and there was no statistical difference between the two groups (P ＞ 0.05).Conclusion Ambroxol hydrochloride added to antibiotic routine therapy in treatment the elderly diabetic patients complicated with pneumonia couldimprove the cure rate and shorten the healing time.It was worthy of clinical application.
